Log of Annotation Updates

3214 annotation updates returned 12345678910..33Next
Ordered by Submitter , ascending

Download options

Date Locus Tag Strain Description Submitter
May 8, 2015 PA2393 Pseudomonas aeruginosa PAO1 New product name: putative dipeptidase. New product name confidence: Class 2.
Sep 30, 2005 PA4999 Pseudomonas aeruginosa PAO1 New gene name: waaL. New protein name: O-antigen ligase, Waal. New protein name confidence: Class 1. New evidence reference (PubMedID: 15838026). New comment: WaaL is important for cell wall integrity and motility of the bacteria. Abeyrathne, P.D., Brinkman, F.S.L., Daniels, C.,Lam, J.S., Lo, R.C., Matewish, M.J., Poon, K.K.H.
Aug 25, 2011 PA14_15830 Pseudomonas aeruginosa UCBPP-PA14 New product name: Transcriptional regulator of N-Acetylglucosamine catabolism operon. New gene name: nagR. New product name confidence: Class 1. New PubMed reference: 21169497. Aishwarya Korgaonkar, The University of Texas at Austin, USA
Aug 25, 2011 PA14_15780 Pseudomonas aeruginosa UCBPP-PA14 New product name: N-Acetyl-D-Glucosamine phosphotransferase system transporter. New gene name: nagE. New PubMed reference: 21169497. Aishwarya Korgaonkar, The University of Texas at Austin, USA
Aug 25, 2011 PALES_12231 Pseudomonas aeruginosa LESB58 New product name: Transcriptional regulator of N-Acetylglucosamine catabolism operon. New gene name: nagR. New product name confidence: Class 1. New PubMed reference: 21169497. Aishwarya Korgaonkar, The University of Texas at Austin, USA
Aug 25, 2011 PA3757 Pseudomonas aeruginosa PAO1 New product name: Transcriptional regulator of N-Acetylglucosamine catabolism operon. New gene name: nagR. New product name confidence: Class 1. New PubMed reference: 21169497. Aishwarya Korgaonkar, The University of Texas at Austin, USA
Aug 25, 2011 PA3761 Pseudomonas aeruginosa PAO1 New gene name: nagE. New PubMed reference: 21169497. Aishwarya Korgaonkar, The University of Texas at Austin, USA
Aug 25, 2011 PALES_12191 Pseudomonas aeruginosa LESB58 New gene name: nagE. New PubMed reference: 21169497. Aishwarya Korgaonkar, The University of Texas at Austin, USA
Jul 17, 2009 PALES_41991 Pseudomonas aeruginosa LESB58 New gene name: tpbB. New product name: diguanylate cyclase TpbB. New product name confidence: Class 1. New function class: Motility & Attachment. New function class: Membrane proteins. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PA14_49890 Pseudomonas aeruginosa UCBPP-PA14 New gene name: tpbB. New product name: diguanylate cyclase TpbB. New product name confidence: Class 1. New function class: Motility & Attachment. New function class: Membrane proteins. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PA1120 Pseudomonas aeruginosa PAO1 New gene name: tpbB. New product name: diguanylate cyclase TpbB. New product name confidence: Class 1. New function class: Motility & Attachment. New function class: Membrane proteins. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PA3885 Pseudomonas aeruginosa PAO1 New gene name: tpbA. New product name: protein tyrosine phosphatase TpbA. New product name confidence: Class 1. New subcellular localization: Periplasm. New subcellular localization confidence: Class 2. New function class: Translation, post-translational modification, degradation. New function class: Motility & Attachment. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PA14_13660 Pseudomonas aeruginosa UCBPP-PA14 New gene name: tpbA. New product name: protein tyrosine phosphatase TpbA. New product name confidence: Class 1. New subcellular localization: Periplasm. New subcellular localization confidence: Class 2. New function class: Translation, post-translational modification, degradation. New function class: Motility & Attachment. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PALES_10931 Pseudomonas aeruginosa LESB58 New gene name: tpbA. New product name: protein tyrosine phosphatase TpbA. New product name confidence: Class 1. New subcellular localization: Periplasm. New subcellular localization confidence: Class 2. New function class: Translation, post-translational modification, degradation. New function class: Motility & Attachment. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PSPA7_1223 Pseudomonas aeruginosa PA7 New gene name: tpbA. New product name: protein tyrosine phosphatase TpbA. New product name confidence: Class 1. New subcellular localization: Periplasm. New subcellular localization confidence: Class 2. New function class: Translation, post-translational modification, degradation. New function class: Motility & Attachment. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 17, 2009 PSPA7_4249 Pseudomonas aeruginosa PA7 New gene name: tpbB. New product name: diguanylate cyclase TpbB. New product name confidence: Class 1. New function class: Motility & Attachment. New function class: Membrane proteins. New evidence reference (PMID): 19543378. Akihiro Ueda, Texas A&M University, USA
Jul 16, 2006 PA4295 Pseudomonas aeruginosa PAO1 New gene name: fppA. New product name: Flp prepilin peptidase A, FppA (previously hypothetical protein). New product name confidence: Class 1 (previously Class 4). New evidence reference (PMID): 16788194. New PseudoCAP function class: Motility and attachment. New homology: 45% similarity to OrfB [Actinobacillus actynomycetemcomitans]. New homology: 42% similarity to CpaA [Caulobacter crescentus]. New genomic context: Outside of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4297 Pseudomonas aeruginosa PAO1 New gene name: tadG (previously blank). New product name: TadG (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4299 Pseudomonas aeruginosa PAO1 New gene name: tadD (previously blank). New product name: TadD (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4300 Pseudomonas aeruginosa PAO1 New gene name: tadC (previously blank). New product name: TadC (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 21% Identity, 48% similarity to TadC [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspF family of proteins Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4301 Pseudomonas aeruginosa PAO1 New gene name: tadB (previously blank). New product name: TadB (previously hypothetical protein). New product name confidence: Class 2 (previously Class 4). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 23% Identity, 46% similarity to TadC [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspF family of proteins Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4302 Pseudomonas aeruginosa PAO1 New gene name: tadA (previously blank). New product name: TadA ATPase (previously designated probable type II secretion system protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 44% Identity, 66% Similarity to TadA [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspE family of traffic ATPases Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4303 Pseudomonas aeruginosa PAO1 New gene name: tadZ (previously blank). New product name: TadZ (previously designated hypothetical protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 25% Identity, 38% Similarity to CpaE [Caulobacter crescentus]. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4304 Pseudomonas aeruginosa PAO1 New gene name: rcpA (previously blank). New product name: RcpA (previously probable type II secretion system protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 33% Identity, 50% Similarity to RcpA [Actinobacillus actinomycetemcomitans]. New structure feature: Belongs to the GspA family of secretins. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4305 Pseudomonas aeruginosa PAO1 New gene name: rcpC (previously blank). New product name: RcpC (previously designated hypothetical protein). New product name confidence: Class 2 (previously Class 3). New evidence reference (PMID): 16788194. New evidence reference (PMID): 15837433. New PseudoCAP function class: Motility and attachment. New genomic context: Part of flp-tad-rcp gene cluster (PA4297-PA4305) required for assembly of Type IVb pilin, Flp. New homology: 26% Identity, 37% similarity to CpaB [Caulobacter crescentus CB15]. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jul 16, 2006 PA4306 Pseudomonas aeruginosa PAO1 New gene name: flp. New product name: Type IVb pilin, Flp (previously hypothetical protein). New product name confidence: Class 1 (previously Class 4). New subcellular localization: Fimbrial. New subcellular localization confidence: Class 1 (localization experimentally demonstrated in P. aeruginosa). New PseudoCAP function class: Motility and attachment. New evidence reference: PMID: 16788194. New genomic context: This ORF is transcribed in a reverse orientation as compared to flp-tad-rcp gene cluster (PA4297-PA4305) responsible for its assembly. Alain Filloux, Centre National de la Recherche Scientifique, Marseille, France
Jan 28, 2014 PA1242 Pseudomonas aeruginosa PAO1 New product name: SprP. New gene name: sprP. New product name confidence: Class 1. New function class: Translation, post-translational modification, degradation. New function class: Motility & Attachment. New PubMed reference: 24376018. Alexander Pelzer, Institute of Molecular Enzyme Technology, Germany
Jul 29, 2010 PA0785 Pseudomonas aeruginosa PAO1 New gene name: azoR1. New product name: FMN-dependent NADH-azoreductase 1, AzoR1. New EC Number: 1.7.-.-. New evidence reference (PMID): 20417637. Ali Ryan,Department of Pharmacology, University of Oxford,UK.
Jul 29, 2010 PA1962 Pseudomonas aeruginosa PAO1 New gene name: azoR2. New product name: FMN-dependent NADH-azoreductase 2, AzoR2. New product name confidence: Class 1. New EC Number: 1.7.-.-. New evidence reference (PMID): 20417637. Ali Ryan,Department of Pharmacology, University of Oxford,UK.
Jul 29, 2010 PA3223 Pseudomonas aeruginosa PAO1 New gene name: azoR3. New product name: AzoR3, azoreductase 3. New product name confidence: Class 1. New EC Number: 1.7.-.-. New evidence reference (PMID): 20417637. Ali Ryan,Department of Pharmacology, University of Oxford,UK.
Dec 11, 2001 PA0336 Pseudomonas aeruginosa PAO1 Annotation of a gene previously described as a conserved hypothetical protein, with alt gene name ygdP. New protein name: Nudix hydrolase YgdP. New alt protein name: dinucleoside oligophosphate pyrophosphatase. New gene name: ygdP. New alt gene name: (now blank). New function: Nucleotide biosynthesis and metabolism. New evidence reference (PubMed ID): 11479323. Alice Erwin, Chiron-Seattle, USA
Sep 23, 2015 PAK_04190 Pseudomonas aeruginosa PAK New gene name: phoQ. New PubMed ID: 21968359. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA4381 Pseudomonas aeruginosa PAO1 New gene name: colR. New product name: two-component response regulator ColR. New PubMed ID: 23459479. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA3077 Pseudomonas aeruginosa PAO1 New PubMed ID: 23459479. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA3078 Pseudomonas aeruginosa PAO1 New PubMed ID: 23459479. Alina Gutu, Harvard University, USA
Sep 23, 2015 PAK_04191 Pseudomonas aeruginosa PAK New gene name: phoP. New PubMed ID: 21968359. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA4776 Pseudomonas aeruginosa PAO1 New PubMed ID: 14702327. New PubMed ID: 22106224. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA4777 Pseudomonas aeruginosa PAO1 New PubMed ID: 14702327. New PubMed ID: 22106224. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA4380 Pseudomonas aeruginosa PAO1 New gene name: colS. New product name: two-component sensor ColS. New PubMed ID: 23459479. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA1179 Pseudomonas aeruginosa PAO1 New PubMed ID: 21968359. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA1180 Pseudomonas aeruginosa PAO1 New PubMed ID: 21968359. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA1559 Pseudomonas aeruginosa PAO1 New PubMed ID: 26100714. Alina Gutu, Harvard University, USA
Sep 23, 2015 PA1560 Pseudomonas aeruginosa PAO1 New PubMed ID: 26100714. Alina Gutu, Harvard University, USA
Aug 25, 2011 PA3946 Pseudomonas aeruginosa PAO1 New product name: Two-component sensor RocS1. New gene name: rocS1. New comment : Overexpression of rocS1 leads to the production of CupB and CupC fimbriae, as well as repression of the MexAB-OprM efflux pump. RocS1 can interact with three response regulators: RocA2 (PA3045), RocA1 (PA3948) and RocR (PA3947).. New comment : Overexpression of rocS1 leads to the production of CupB and CupC fimbriae, as well as repression of the MexAB-OprM efflux pump. RocS1 can interact with three response regulators: RocA2 (PA3045), RocA1 (PA3948) and RocR (PA3947).. New PubMed reference: 15659157. New PubMed reference: 17293418. New PubMed reference: 21205015. Allain Filloux, Imperial College London
Aug 25, 2011 PA3947 Pseudomonas aeruginosa PAO1 New comment : RocR has been shown to have c-di-GMP phosphodiesterase activity and to repress the expression of the cupB and cupC gene clusters.. New comment : Genetic and bacterial two hybrid studies in Pseudomonas aeruginosa PAK have revealed that RocS1-induced expression of the cupB and cupC gene clusters is repressed by RocR. Furthermore, purified RocR has been shown to display phosphodiesterase activity and degrades the second messenger c-di-GMP.. New PubMed reference: 18344366. New PubMed reference: 21205015. Allain Filloux, Imperial College London
Aug 25, 2011 PA3948 Pseudomonas aeruginosa PAO1 New product name: Two-component response regulator RocA1. New comment : RocA1 can interact with two sensors, RocS1 (PA3946) and RocS2 (PA3044) and activates transcription of the cupC gene cluster.. New comment : Functional studies in Pseudomonas aeruginosa PAK have shown that overexpression of RocA1 activates transcription of the cupC gene cluster, which leads to the production and assembly of CupC fimbriae on the cell surface and increases biofilm formation. Genetic and bacterial two hybrid analyses have shown that RocA1 can be activated by the RocS1 sensor, as well as the paralogous RocS2 sensor (PA3044).. New PubMed reference: 15659157. New PubMed reference: 21205015. Allain Filloux, Imperial College London
Aug 25, 2011 PA3044 Pseudomonas aeruginosa PAO1 New product name: Two-component sensor RocS2. New gene name: rocsS2. New product name confidence: Class 1. New comment : Overexpression of rocS2 leads to the production of CupB and CupC fimbriae, as well as repression of the MexAB-OprM efflux pump. RocS2 can interact with three response regulators: RocA2 (PA3045), RocA1 (PA3948) and RocR (PA3947).. New comment : Functional studies in Pseudomonas aeruginosa PAK have shown that RocS2 is part of a signalling network that induces the expression of the cupB and cupC gene clusters, leading to the production and assembly of two distinct types of fimbriae on the cell surface and increases biofilm formation. Expression of rocS2 also represses the expression of the mexAB-oprM gene cluster, leading to increased sensitivity to ?-lactams and other antibiotics. This signalling network involves at least three response regulators: RocA1 (PA3948), RocA2 (PA3045) and RocR (PA3947). Genetic and bacterial two hybrid analyses have shown that RocS2 signals through all three response regulators.. New PubMed reference: 15659157. New PubMed reference: 21205015. Allain Filloux, Imperial College London
Aug 25, 2011 PA3045 Pseudomonas aeruginosa PAO1 New product name: Two-component response regulator, RocA2. New gene name: rocA2. New product name confidence: Class 1. New comment : RocA2 can interact with two sensors, RocS1 (PA3946) and RocS2 (PA3044). Signalling by RocS1 and RocS2 through RocA2 and leads to repression of the mexAB-oprM gene cluster and increased sensitivity to antibiotics.. New comment : Bacterial two hybrid studies in Pseudomonas aeruginosa PAK have shown that RocS1 and RocS2 can both interact with RocA2. Furthermore, a microarray study of PAK and PAK?rocA2, both overexpressing rocS2, revealed that RocA2 represses the expression of the mexAB-oprM gene cluster. qRT-PCR studies confirmed that the same signalling can be achieved by overexpressing rocS1, and in both cases the repression of mexAB-oprM led to an increased sensitivity to antibiotics.. New PubMed reference: 21205015. Allain Filloux, Imperial College London
Aug 25, 2011 PA0033 Pseudomonas aeruginosa PAO1 New product name: Histidine phosphotransfer protein HptC. New gene name: hptC. New product name confidence: Class 2. New function class: Two-component regulatory systems. New GO Accession: GO:0009927(ISS). New PubMed reference: 11121759. Allain Filloux, Imperial College London
Aug 25, 2011 PA0991 Pseudomonas aeruginosa PAO1 New product name: Histidine phosphotransfer protein HptA. New gene name: hptA. New product name confidence: Class 2. New function class: Two-component regulatory systems. New GO Accession: GO:0009927(ISS). New PubMed reference: 11121759. Allain Filloux, Imperial College London
Aug 25, 2011 PA3345 Pseudomonas aeruginosa PAO1 New product name: Histidine phosphotransfer protein HptB. New gene name: hptB. New product name confidence: Class 1. New comment : Using in vitro phosphorylation and bacterial two hybrid analysis, Lin et al. and Hsu et al. subsequently showed that HptB can be phosphorylated by four hybrid sensors, PA1611, PA1976, PA2824 and RetS, and that HptB can transfer a phosphate onto the adjacent response regulator PA3346.. New comment : using genetic, bacterial two hybrid and biochemical analyses, Bordi et al. showed that HptB actually has a negative effect on the activity of the PA3346 response regulator, the function of which is to activate the anti-?-factor PA3347.. New comment : . It was further shown that the HptB signalling pathway intersects the GacA signalling pathway that inversely controls the expression the pel genes involved in biofilm formation and the type III secretion system.. New function class: Two-component regulatory systems. New GO Accession: GO:0009927(IDA). New PubMed reference: 11121759. New PubMed reference: 16182517. New PubMed reference: 18256026. New PubMed reference: 20398205. Allain Filloux, Imperial College London
Aug 25, 2011 PA4648 Pseudomonas aeruginosa PAO1 New product name: Pilin subunit CupE1. New gene name: cupE1. New product name confidence: Class 1. New comment : The cupE gene cluster encodes a chaperone usher pathway that is homologous to the A. baumanii csu gene cluster. Activation of the cupE genes leads to the production and assembly of CupE fimbriae on the cell surface. These fimbriae are important in early and late stages of biofilm formation. The expression of the cupE gene cluster is controlled by the two-component system PprA-PprB, and binding of PprB to the cupE1 promoter has been confirmed by EMSA.. New function class: Cell wall / LPS / capsule. New function class: Motility & Attachment. New PubMed reference: 21091863. Allain Filloux, Imperial College London
Aug 25, 2011 PA4649 Pseudomonas aeruginosa PAO1 New product name: Pilin subunit CupE2. New gene name: cupE2. New product name confidence: Class 1. New comment : The cupE gene cluster encodes a chaperone usher pathway that is homologous to the A. baumanii csu gene cluster. Activation of the cupE genes leads to the production and assembly of CupE fimbriae on the cell surface. These fimbriae are important in early and late stages of biofilm formation. The expression of the cupE gene cluster is controlled by the two-component system PprA-PprB, and binding of PprB to the cupE1 promoter has been confirmed by EMSA.. New function class: Cell wall / LPS / capsule. New function class: Motility & Attachment. New PubMed reference: 21091863. Allain Filloux, Imperial College London
Aug 25, 2011 PA4650 Pseudomonas aeruginosa PAO1 New product name: Pilin subunit CupE3. New gene name: cupE3. New product name confidence: Class 1. New comment : The cupE gene cluster encodes a chaperone usher pathway that is homologous to the A. baumanii csu gene cluster. Activation of the cupE genes leads to the production and assembly of CupE fimbriae on the cell surface. These fimbriae are important in early and late stages of biofilm formation. The expression of the cupE gene cluster is controlled by the two-component system PprA-PprB, and binding of PprB to the cupE1 promoter has been confirmed by EMSA.. New function class: Cell wall / LPS / capsule. New function class: Motility & Attachment. New PubMed reference: 21091863. Allain Filloux, Imperial College London
Aug 25, 2011 PA4651 Pseudomonas aeruginosa PAO1 New product name: Pilin assembly chaperone CupE4. New gene name: cupE4. New product name confidence: Class 1. New comment : The cupE gene cluster encodes a chaperone usher pathway that is homologous to the A. baumanii csu gene cluster. Activation of the cupE genes leads to the production and assembly of CupE fimbriae on the cell surface. These fimbriae are important in early and late stages of biofilm formation. The expression of the cupE gene cluster is controlled by the two-component system PprA-PprB, and binding of PprB to the cupE1 promoter has been confirmed by EMSA.. New function class: Cell wall / LPS / capsule. New PubMed reference: 21091863. Allain Filloux, Imperial College London
Aug 25, 2011 PA4652 Pseudomonas aeruginosa PAO1 New product name: Fimbrial usher protein CupE5. New gene name: cupE5. New product name confidence: Class 1. New comment : The cupE gene cluster encodes a chaperone usher pathway that is homologous to the A. baumanii csu gene cluster. Activation of the cupE genes leads to the production and assembly of CupE fimbriae on the cell surface. These fimbriae are important in early and late stages of biofilm formation. The expression of the cupE gene cluster is controlled by the two-component system PprA-PprB, and binding of PprB to the cupE1 promoter has been confirmed by EMSA.. New function class: Cell wall / LPS / capsule. New function class: Motility & Attachment. New PubMed reference: 21091863. Allain Filloux, Imperial College London
Aug 25, 2011 PA4653 Pseudomonas aeruginosa PAO1 New product name: Adhesin-like protein CupE6. New gene name: cupE6. New product name confidence: Class 1. New comment : The cupE gene cluster encodes a chaperone usher pathway that is homologous to the A. baumanii csu gene cluster. Activation of the cupE genes leads to the production and assembly of CupE fimbriae on the cell surface. These fimbriae are important in early and late stages of biofilm formation. The expression of the cupE gene cluster is controlled by the two-component system PprA-PprB, and binding of PprB to the cupE1 promoter has been confirmed by EMSA.. New function class: Cell wall / LPS / capsule. New function class: Motility & Attachment. New PubMed reference: 21091863. Allain Filloux, Imperial College London
Jan 10, 2008 PA3064 Pseudomonas aeruginosa PAO1 New product name: PelA (Existing value: hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New evidence reference (PMID): 15758243. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Cell wall / LPS / capsule. Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jan 10, 2008 PA3063 Pseudomonas aeruginosa PAO1 New product name: PelB (Existing value: hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New evidence reference (PMID): 15758243. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Cell wall / LPS / capsule. Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jan 10, 2008 PA3062 Pseudomonas aeruginosa PAO1 New product name: PelC (Existing value: hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New evidence reference (PMID): 15758243. New evidence reference (PMID): 17524545. New subcellular localization: Outer membrane (Existing value: Unknown). New subcellular localization confidence: Class 1 (Existing value: Class 3). New PseudoCAP function class: Cell wall / LPS / capsule. Deleting function class: Hypothetical, unclassified, unknown. Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jan 10, 2008 PA3061 Pseudomonas aeruginosa PAO1 New product name: PelD (Existing value: hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New evidence reference (PMID): 15758243. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Cell wall / LPS / capsule. New evidence reference (PMID): 17824927. New structure feature: RxxD motif (required for pellicle synthesis). New structure feature: c-di-GMP binding site. Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jan 10, 2008 PA3060 Pseudomonas aeruginosa PAO1 New product name: PelE (Existing value: hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). New evidence reference (PMID): 15758243. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Cell wall / LPS / capsule. Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jan 10, 2008 PA3059 Pseudomonas aeruginosa PAO1 New evidence reference (PMID): 15758243. Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Cell wall / LPS / capsule. New product name confidence: Class 1 (Existing value: Class 4). New product name: PelF (Existing value: hypothetical protein). New comment: PelF is a putative glycosyltransferase from the GT4 family. Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jan 10, 2008 PA3058 Pseudomonas aeruginosa PAO1 New product name: PelG (Existing value: hypothetical protein). New product name confidence: Class 1 (Existing value: Class 4). Deleting function class: Hypothetical, unclassified, unknown. New PseudoCAP function class: Cell wall / LPS / capsule. New evidence reference (PMID): 15758243. New comment: PelG is a putative member of the PST family (Polysaccharide transporter). Allain Filloux, Laboratoire d'Ingenierie des Systemes Macromoleculaires, Marseille cedex, France
Jul 29, 2010 PA4726.11 Pseudomonas aeruginosa PAO1 New feature: PA4726.11. Feature type ncRNA. New nucleotide sequence for upstream 500 bp. New function class: Non-coding RNA gene. New function class: Transcriptional regulators. New evidence reference (PMID): 19959660. Amy Yeung, Hancock Lab, University of British Columbia, Canada.
Jul 29, 2010 PA4724.1 Pseudomonas aeruginosa PAO1 New feature: PA4724.1. Feature type . New nucleotide sequence for upstream 500 bp. New comment: Coordinates predicted using GLIMMER (version 3.02). New function class: Hypothetical, unclassified, unknown. Amy Yeung, Hancock Lab, University of British Columbia, Canada.
Aug 26, 2010 PA0406 Pseudomonas aeruginosa PAO1 New gene name: tonB3. New product name: TonB3. New product name confidence: Class 1. New function class: Motility & Attachment. New evidence reference (PMID): 15205442. Ana Misic, University of Wisconsin-Madison
Jan 20, 2017 PA0321 Pseudomonas aeruginosa PAO1 New product name: acetylpolyamine amidohydrolase. New product name confidence: Class 1. New PubMed ID: 24871864. New PubMed ID: 26956223. Andreas Kraemer, Ecologic Institute, Berlin
Jan 20, 2017 PA1409 Pseudomonas aeruginosa PAO1 New product name confidence: Class 1. New PubMed ID: 24871864. New PubMed ID: 26956223. Andreas Kraemer, Ecologic Institute, Berlin
Jan 20, 2017 PA3774 Pseudomonas aeruginosa PAO1 New product name: histone deacetylase-like amidohydrolase. New product name confidence: Class 2. New PubMed ID: 24871864. New PubMed ID: 26956223. Andreas Kraemer, Ecologic Institute, Berlin
Jan 28, 2014 PA4737 Pseudomonas aeruginosa PAO1 New comment : Initiation codon of PA4737 overlaps with stop codon of PA4736. This is such that the first and second bases of the initiation codon are shared with the first and second bases of the termination codon. As a result of the tetranucleotide sequence TTGA, which is termed stop-start codon, the translation of the PA4737 gene may be directly linked to that of PA4736 through -1 frame shifting.. Andrew Chibeu, Canadian Research Institute for Food Safety
Jun 19, 2007 PA2412 Pseudomonas aeruginosa PAO1 New structure feature: PDB Accession: 2PST. Andrew Gulick, Hauptman-Woodward Institute, Buffalo, NY, USA.
Jul 29, 2010 PA2254 Pseudomonas aeruginosa PAO1 New product name: paerucumarin biosynthesis protein PvcA. New function class: Amino acid biosynthesis and metabolism. New pathway: paerucumarin biosynthesis. New pathway: isonitrile biosynthesis. New evidence reference (PMID): 18689486. New evidence reference (PMID): 18824174. Andrew Gulick,State University of New York at Buffalo, USA
Jul 29, 2010 PA2255 Pseudomonas aeruginosa PAO1 New product name: paerucumarin biosynthesis protein PvcB. New function class: Amino acid biosynthesis and metabolism. New pathway: paerucumarin biosynthesis. New pathway: isonitrile biosynthesis. New evidence reference (PMID): 18689486. New evidence reference (PMID): 18824174. Andrew Gulick,State University of New York at Buffalo, USA
Jul 29, 2010 PA2256 Pseudomonas aeruginosa PAO1 New product name: paerucumarin biosynthesis protein PvcC. New function class: Amino acid biosynthesis and metabolism. New pathway: paerucumarin biosynthesis. New pathway: isonitrile biosynthesis. New evidence reference (PMID): 18689486. Andrew Gulick,State University of New York at Buffalo, USA
Jul 29, 2010 PA2257 Pseudomonas aeruginosa PAO1 New product name: paerucumarin biosynthesis protein PvcD. New function class: Amino acid biosynthesis and metabolism. New pathway: paerucumarin biosynthesis. New pathway: isonitrile biosynthesis. New evidence reference (PMID): 18689486. Andrew Gulick,State University of New York at Buffalo, USA
Nov 6, 2013 PA4600 Pseudomonas aeruginosa PAO1 New translation start site: 5155525. New PubMed reference: 23924707. Andrew Purssell & Keith Poole, Queen's University, Canada
Mar 5, 2012 PA4921 Pseudomonas aeruginosa PAO1 New product name: acetylcholinesterase, AchE. New gene name: achE. New product name confidence: Class 1. New EC Number: 3.1.1.7. New GO Accession: GO:0003990(IDA). New PubMed reference: 22192836. Angela T Lisa, Universidad Nacional de Río Cuarto, Argentina
Nov 24, 2014 PA4704.2 Pseudomonas aeruginosa PAO1 Changed start site from 5284172 to correct start site 5284206 given in PubMed reference 15210934. Angela Wilks, University of Maryland
Nov 24, 2014 PA4704.1 Pseudomonas aeruginosa PAO1 New PubMed ID: 15210934. Angela Wilks, University of Maryland
Nov 24, 2014 PA4704.3 Pseudomonas aeruginosa PAO1 New product name confidence: Class 1. New PubMed ID: 20386693. New PseudoCAP function class: Non-coding RNA gene. New comment: 325-nucleotide non-coding RNA that is regulated by heme and encompasses the prrF1, prrF2 genes. Angela Wilks, University of Maryland
Nov 24, 2014 PA4707 Pseudomonas aeruginosa PAO1 New gene name: phuU. New product name name: PhuU. New product name confidence: Class 1. New PubMed ID: 10658665. Angela Wilks, University of Maryland
Nov 24, 2014 PA4706 Pseudomonas aeruginosa PAO1 New gene name: phuV. New product name name: PhuV. New product name confidence: Class 1. New PubMed ID: 10658665. Angela Wilks, University of Maryland
Nov 24, 2014 PA4705 Pseudomonas aeruginosa PAO1 New gene name: phuW. New product name name: PhuW. New product name confidence: Class 2. New PubMed ID: 10658665. Angela Wilks, University of Maryland
Nov 24, 2014 PA4709 Pseudomonas aeruginosa PAO1 New gene name: phuS. New product name name: PhuS. New product name confidence: Class 1. New PubMed ID: 10658665. New PubMed ID: 22451925. New PubMed ID: 23947366. Angela Wilks, University of Maryland
Nov 24, 2014 PA0513 Pseudomonas aeruginosa PAO1 New gene name: nirG. New product name name: NirG. New product name confidence: Class 1. New PubMed ID: 8982003. Angela Wilks, University of Maryland
Nov 24, 2014 PA0512 Pseudomonas aeruginosa PAO1 New gene name: nirH. New product name name: NirH. New product name confidence: Class 1. New PubMed ID: 8982003. Angela Wilks, University of Maryland
Nov 24, 2014 PA0510 Pseudomonas aeruginosa PAO1 New gene name: nirE. New product name name: NirE. New product name confidence: Class 1. New PubMed ID: 19754882. New PubMed ID: 8982003. Angela Wilks, University of Maryland
Nov 24, 2014 PA1705 Pseudomonas aeruginosa PAO1 Correction for translation start site. Changed from 1851982 to 1851991 based on PMID:20487288. Arne Rietsch, Case Western Reserve University, USA
Nov 24, 2014 PA1705 Pseudomonas aeruginosa PAO1 New PubMed ID: 20487288. Arne Rietsch, Case Western Reserve University, USA
Jul 1, 2006 PA1091 Pseudomonas aeruginosa PAO1 New gene name: fgtA. New product name: flagellar glycosyl transferase, FgtA. New product name rating: Class 1. New homology: 53% similar to orfN [P. aeruginosa PAK]. New genomic context: Upstream of FliC and FlaG homologs, as in the Riftia pachyptila endosymbiont. New evidence reference: Verma, Amrisha , Schirm, Michael , Arora, Shiwani K., Thibault, P , Logan, Susan M., Ramphal, Reuben Glycosylation of b-type flagellin of Pseudomonas aeruginosa: structural and genetic basis (unpublished). Arora,SK, Logan,SM, Ramphal,R, Schirm,M, Thibault,P and A Verma.
Mar 1, 2006 PA0337 Pseudomonas aeruginosa PAO1 New comment: ptsP has an important role in the negative regulation of pyocyanin production via the expression of qscR. New evidence reference (Pubmed ID): 16239083. New product name confidence: Class 1. Bai, Y.,Bai, F.,Li, Y.,Lin, W.,RC.,Qiao, M.,Saris, P.,Xia, H.,Xu, S.,Xu, H.,Yao, H.,and X. Zhang. Submission made to database by Brinkman, F.S.L. and R.C. Lo after consulting with authors of paper.
Nov 9, 2004 PA4856 Pseudomonas aeruginosa PAO1 Annotation of gene previously described as probable sensor/response regulator hybrid (Class 3). New gene name: rtsM. New protein name: RtsM. New protein name confidence: Class 1. Barbara Kazmierczak, Yale University, USA
Sep 30, 2005 PA5292 Pseudomonas aeruginosa PAO1 New subcellular localization prediction: Periplasmic. New subcellular localization confidence: Class 1. New Protein name confidence: Class 1. New evidence reference (PMID): 15886911. Barra, J.L., Beassoni, P., Domenech, C.E., Forrellad, M., Garrido, M.N., Lisa, A.T., Massimelli, M.J. Universidad Nacional de Rio Cuarto, Rio Cuarto
Mar 1, 2006 PA4168 Pseudomonas aeruginosa PAO1 New gene name: fpvB. New product name: second ferric pyoverdine receptor FpvB. New product name confidence: Class 1. New evidence reference (Pubmed ID): 15184553. New comment: Iron limitation induces transcription of fpvA and fpvB. Beatson, SA., Cornelis, P.,Dieu, BTM.,Ghysels, B.,Ochsner, UA.,Pirnay, J-P. and ML. Vasil. Submission made to database by Brinkman, F.S.L. and R.C. Lo after consulting with authors of paper.
Mar 5, 2016 PA2005 Pseudomonas aeruginosa PAO1 New gene name: hbcR. New product name: HbcR. New product name synonym: (R)-3-hydroxybutyrate catabolism regulator. New product name confidence: Class 1. New PubMed ID: 26311173. Benjamin Lundgren, SUNY College of Environmental Science and Forestry
Sep 30, 2005 PA4827 Pseudomonas aeruginosa PAO1 New alternate gene name: nat. New protein name: arylamine N-acetyltransferase. New protein name confidence: Class 1. New alternate protein name: NAT. New evidence reference (PMID: 15447630). New homology: 50% similar to nat protein [Mycobacterium smegmatis] ; 43% similar to nat protein [Mesorhizobium loti] ; 43% similar to nat protein [Mycobacterium tuberculosis]. New comment: PA4827 has been cloned, expressed, characterised and crystallised. The crystal structure (PDB 1w4t) shows very similar fold to the nat protein from M. smegmatis, with rmsd of 1.3 Angstroms over 240 equivalent atoms. Bhakta, S., Dupret, J.-M., Holton, S.J., Noble, M.E.M.,Rodrigues-Lima, F., Sim, E., Westwood, I.M. University of Oxford. UK.
Jul 30, 2003 PA4959 Pseudomonas aeruginosa PAO1 Annotation of gene previously described as a conserved hypothetical protein, with no gene name. New alternate protein name: FimX. New alternate gene name: fimX. New function:Motility and Attachment (unpublished data). Bixing Huang, University of Queensland, Brisbane, Australia
May 12, 2005 PA5541 Pseudomonas aeruginosa PAO1 New gene name: pyrQ. New alternate gene name: pyrC2. New protein name: dihydroorotase. New protein name confidence: Class 1. New evidence reference (Pubmed ID): 1527824. New comment: Deletion of pyrC and pyrC2 (pyrQ) results in pyrimidine auxotrophy; gene name changed from pyrC2 to pyrQ to conform with naming standards. Brichta, D M., Azad, K N., Ralli, P, O'Donovan, G A., Fields C.J., University of North Texas, USA
Jul 1, 2006 PA2234 Pseudomonas aeruginosa PAO1 New subcellular localization: Extracellular. New subcellular localization rating: Class 1. New evidence reference: 16598021. Brinkman, FSL, Campisano,A, Lo, RC,Overhage,J, Rehm,BHA, Schemionek,M, Schroeder,C.
3214 annotation updates returned 12345678910..33Next