Pseudomonas aeruginosa PAO1, PA0041

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0041
Name
Replicon chromosome
Genomic location 42914 - 53521 (+ strand)
Transposon Mutants 10 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_248731.1
GI 15595239
Affymetrix PA0041_at
Entrez 878601
GenBank AAG03431.1
INSDC AAG03431.1
NCBI Locus Tag PA0041
protein_id(GenBank) gb|AAG03431.1|AE004443_9|gnl|PseudoCAP|PA0041
TIGR NTL03PA00042
UniParc UPI00000C4EFB
UniProtKB Acc Q9I791
UniProtKB ID Q9I791_PSEAE
UniRef100 UniRef100_Q9I791
UniRef50 UniRef50_Q9I791
UniRef90 UniRef90_Q9I791

Product

Feature Type CDS
Coding Frame 1
Product Name
probable hemagglutinin
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -43.99
Kyte-Doolittle Hydrophobicity Value -0.192
Molecular Weight (kDa) 361.6
Isoelectric Point (pI) 5.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database Victors : 4221
Category probable hemagglutinin
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Rattus norvegicus
Notes
Infection model Rat agar bead model of chronic lung infection
Reference 14641575

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 73 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000041 (609 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0041

Human Homologs

References

Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence.
Relman DA, Domenighini M, Tuomanen E, Rappuoli R, Falkow S
Proc Natl Acad Sci U S A 1989 Apr;86(8):2637-41
PubMed ID: 2539596