Pseudomonas aeruginosa PAO1, PA0074 (ppkA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004674 protein serine/threonine kinase activity
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
9852028 Reviewed by curator
Biological Process GO:0050714 positive regulation of protein secretion
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
19400797 Reviewed by curator
Molecular Function GO:0004672 protein kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00220
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006468 protein phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00220
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00220
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class
Adaptation, Protection Other PAO1 genes in this class
Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03070 Bacterial secretion system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00198 vWFA - - 616 797 2.85477E-12
SMART SM00327 VWA_4 IPR002035 von Willebrand factor, type A 613 804 2.5E-9
SUPERFAMILY SSF56112 Protein kinase-like (PK-like) IPR011009 Protein kinase-like domain superfamily 6 339 1.48E-76
SUPERFAMILY SSF53300 vWA-like IPR036465 von Willebrand factor A-like domain superfamily 615 793 2.23E-12
Pfam PF00092 von Willebrand factor type A domain IPR002035 von Willebrand factor, type A 616 780 1.5E-5
MobiDBLite mobidb-lite consensus disorder prediction - - 316 347 -
PANTHER PTHR43289 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED - - 5 564 7.2E-84
MobiDBLite mobidb-lite consensus disorder prediction - - 381 417 -
SMART SM00220 serkin_6 IPR000719 Protein kinase domain 8 263 5.1E-66
Gene3D G3DSA:3.40.50.410 von Willebrand factor, type A domain IPR036465 von Willebrand factor A-like domain superfamily 614 769 5.9E-12
Pfam PF00069 Protein kinase domain IPR000719 Protein kinase domain 9 250 3.9E-50
Gene3D G3DSA:3.30.200.20 Phosphorylase Kinase; domain 1 - - 2 87 3.6E-29
MobiDBLite mobidb-lite consensus disorder prediction - - 586 606 -
CDD cd14014 STKc_PknB_like - - 7 261 6.97485E-108
PANTHER PTHR43289:SF18 SERINE/THREONINE-PROTEIN KINASE PRKC - - 5 564 7.2E-84
Gene3D G3DSA:1.10.510.10 Transferase(Phosphotransferase) domain 1 - - 88 274 1.8E-48
MobiDBLite mobidb-lite consensus disorder prediction - - 276 351 -
MobiDBLite mobidb-lite consensus disorder prediction - - 281 299 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.