Pseudomonas aeruginosa PAO1, PA1243

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 490 558 4.32E-11
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 75 175 5.76E-6
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 552 722 2.23E-37
SMART SM00086 pac_2 IPR001610 PAC motif 414 456 3.2E-7
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 334 454 4.01E-22
CDD cd16919 HATPase_CckA-like - - 607 719 1.28434E-61
Gene3D G3DSA:3.30.450.20 PAS domain - - 343 475 9.9E-24
Coils Coil Coil - - 456 487 -
Gene3D G3DSA:3.30.450.40 - IPR029016 GAF-like domain superfamily 177 342 6.5E-9
Gene3D G3DSA:3.30.450.20 PAS domain - - 53 176 4.7E-21
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 496 561 4.8E-9
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 497 559 7.4E-9
SMART SM00091 pas_2 IPR000014 PAS domain 345 411 7.3E-7
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 682 700 1.5E-14
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 342 463 2.4E-14
CDD cd18161 REC_hyHK_blue-like - - 744 841 2.55849E-36
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 744 850 7.8E-17
SUPERFAMILY SSF55781 GAF domain-like - - 171 337 2.4E-15
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 494 557 1.59998E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 706 719 1.5E-14
PANTHER PTHR43065 SENSOR HISTIDINE KINASE - - 337 727 5.6E-73
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 741 855 7.97E-28
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 651 665 1.5E-14
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 742 850 1.8E-22
Pfam PF08448 PAS fold IPR013656 PAS fold-4 351 458 1.5E-11
SMART SM00086 pac_2 IPR001610 PAC motif 126 169 26.0
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 602 722 1.7E-24
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 562 731 1.9E-40
Gene3D G3DSA:3.40.50.2300 - - - 742 858 6.2E-26
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 669 679 1.5E-14
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 604 720 3.9E-16
Gene3D G3DSA:1.10.287.130 - - - 488 560 1.3E-17
CDD cd00130 PAS IPR000014 PAS domain 354 453 7.04961E-11
Pfam PF08448 PAS fold IPR013656 PAS fold-4 74 171 1.6E-7

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.