Pseudomonas aeruginosa PAO1, PA3159 (wbpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0047004 UDP-N-acetylglucosamine 6-dehydrogenase activity
EXP
Inferred from Experiment
ECO:0000269
experimental evidence used in manual assertion
15226302 Reviewed by curator
Biological Process GO:0009243 O antigen biosynthetic process
EXP
Inferred from Experiment
ECO:0000269
experimental evidence used in manual assertion
18621892 Reviewed by curator
Molecular Function GO:0003954 NADH dehydrogenase activity
EXP
Inferred from Experiment
ECO:0000269
experimental evidence used in manual assertion
18621892 Reviewed by curator
Biological Process GO:0000271 polysaccharide biosynthetic process
IDA
Inferred from Direct Assay
ECO:0000314
direct assay evidence used in manual assertion
15226302 Reviewed by curator
Biological Process GO:0000271 polysaccharide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500136
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000124
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF500136
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00984
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class
Putative enzymes Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00520 Amino sugar and nucleotide sugar metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP UDP-2,3-diacetamido-2,3-dideoxy-d-mannuronic acid biosynthesis pathway ECO:0000037
not_recorded
PseudoCAP Lipopolysaccharide biosynthesis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF000124 UDPglc_GDPman_dh IPR017476 UDP-glucose/GDP-mannose dehydrogenase 17 435 5.1E-55
NCBIfam TIGR03026 JCVI: nucleotide sugar dehydrogenase IPR017476 UDP-glucose/GDP-mannose dehydrogenase 18 423 8.3E-127
PANTHER PTHR43491 UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase 9 432 0.0
SUPERFAMILY SSF48179 6-phosphogluconate dehydrogenase C-terminal domain-like IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 212 305 1.36E-29
Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal 18 192 3.6E-50
Gene3D G3DSA:3.40.50.720 - - - 3 209 1.2E-53
FunFam G3DSA:3.40.50.720:FF:000727 UDP-N-acetyl-D-glucosamine dehydrogenase - - 211 434 0.0
SMART SM00984 UDPG_MGDP_dh_C_a_2_a IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 330 428 6.5E-31
Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal 330 424 3.7E-21
PIRSF PIRSF500136 UDP_ManNAc_DH IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase 6 435 0.0
Gene3D G3DSA:3.40.50.720 - - - 211 433 3.8E-58
SUPERFAMILY SSF52413 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily 317 427 2.09E-26
Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation 213 303 1.6E-28
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 18 206 4.79E-41

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.