Pseudomonas aeruginosa UCBPP-PA14, PA14_00050 (gyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 221 243 1.8E-83
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 4 221 1.1E-94
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 376 396 1.8E-83
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 7 219 5.24E-75
FunFam G3DSA:3.10.20.690:FF:000002 DNA gyrase subunit B - - 595 684 1.1E-43
SUPERFAMILY SSF54211 Ribosomal protein S5 domain 2-like IPR020568 Ribosomal protein uS5 domain 2-type superfamily 222 394 2.85E-57
Gene3D G3DSA:3.40.50.670 - IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal 705 806 1.5E-28
CDD cd00822 TopoII_Trans_DNA_gyrase - - 221 379 3.86198E-75
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 244 262 1.8E-83
FunFam G3DSA:3.40.50.670:FF:000005 DNA gyrase subunit B - - 393 593 6.3E-124
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 197 210 1.8E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 759 771 1.8E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 7 17 1.8E-83
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 34 176 2.3E-22
NCBIfam TIGR01059 JCVI: DNA gyrase subunit B IPR011557 DNA gyrase, subunit B 7 806 0.0
Pfam PF18053 DNA gyrase B subunit insert domain IPR041423 DNA gyrase subunit B insert domain 566 732 2.3E-51
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 33 177 2.5E-30
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 182 197 1.8E-83
Gene3D G3DSA:3.10.20.690 - - - 595 684 1.5E-26
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 472 481 1.8E-83
Pfam PF01751 Toprim domain IPR006171 TOPRIM domain 421 533 1.4E-17
Hamap MF_01898 DNA gyrase subunit B [gyrB]. IPR011557 DNA gyrase, subunit B 4 806 101.230545
PRINTS PR00418 DNA topoisomerase II family signature - - 72 85 9.7E-72
Gene3D G3DSA:3.40.50.670 - IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal 399 591 2.1E-75
PRINTS PR00418 DNA topoisomerase II family signature - - 270 283 9.7E-72
PRINTS PR00418 DNA topoisomerase II family signature - - 527 539 9.7E-72
FunFam G3DSA:3.30.230.10:FF:000005 DNA gyrase subunit B - - 221 394 4.0E-77
SUPERFAMILY SSF56719 Type II DNA topoisomerase IPR013760 DNA topoisomerase, type IIA-like domain superfamily 396 796 2.59E-88
PANTHER PTHR45866 DNA GYRASE/TOPOISOMERASE SUBUNIT B - - 3 805 0.0
Gene3D G3DSA:3.30.230.10 - IPR014721 Small ribosomal subunit protein uS5 domain 2-type fold, subgroup 222 398 4.5E-66
FunFam G3DSA:3.40.50.670:FF:000004 DNA gyrase subunit B - - 706 805 1.4E-48
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 314 330 1.8E-83
SMART SM00433 topII5 IPR001241 DNA topoisomerase, type IIA 37 799 0.0
PRINTS PR00418 DNA topoisomerase II family signature - - 507 524 9.7E-72
PRINTS PR00418 DNA topoisomerase II family signature - - 489 505 9.7E-72
PRINTS PR00418 DNA topoisomerase II family signature - - 422 436 9.7E-72
CDD cd16928 HATPase_GyrB-like - - 38 217 3.79656E-105
FunFam G3DSA:3.30.565.10:FF:000002 DNA gyrase subunit B - - 4 220 3.9E-96
Pfam PF00204 DNA gyrase B IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 222 392 9.2E-57
Pfam PF00986 DNA gyrase B subunit, carboxyl terminus IPR002288 DNA gyrase B subunit, C-terminal 734 795 8.2E-31
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 775 791 1.8E-83
PRINTS PR00418 DNA topoisomerase II family signature - - 115 129 9.7E-72
CDD cd03366 TOPRIM_TopoIIA_GyrB IPR034160 DNA gyrase subunit B, TOPRIM domain 420 534 1.34844E-79
PRINTS PR00418 DNA topoisomerase II family signature - - 738 754 9.7E-72
PRINTS PR00418 DNA topoisomerase II family signature - - 37 52 9.7E-72
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 362 376 1.8E-83

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.