Pseudomonas aeruginosa UCBPP-PA14, PA14_00990 (tssA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_00990
Name
tssA1
Replicon chromosome
Genomic location 97777 - 98811 (+ strand)
Transposon Mutants in orthologs 7 transposon mutants in orthologs
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)

Cross-References

RefSeq YP_788239.1
GI 116053802
Entrez 4380428
INSDC ABJ15038.1
NCBI Locus Tag PA14_00990
UniParc UPI0000396C17
UniProtKB Acc Q02UZ7
UniProtKB ID Q02UZ7_PSEAB
UniRef100 UniRef100_Q02UZ7
UniRef50 UniRef50_Q4K3N9
UniRef90 UniRef90_Q9I750

Product

Feature Type CDS
Coding Frame 1
Product Name
TssA1
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -22.53
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 36.6
Isoelectric Point (pI) 4.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 81 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000081 (1178 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_00990
Search term: tssA1
Search term: TssA1

Human Homologs

References

TssA forms a gp6-like ring attached to the type VI secretion sheath.
Planamente S, Salih O, Manoli E, Albesa-Jové D, Freemont PS, Filloux A
EMBO J 2016 Aug 1;35(15):1613-27
PubMed ID: 27288401
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999