Pseudomonas aeruginosa UCBPP-PA14, PA14_01140 (tse6)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
| Locus Tag |
PA14_01140
|
| Name |
tse6
|
| Replicon | chromosome |
| Genomic location | 111195 - 112514 (- strand) |
| Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
| Transposon Mutants in orthologs | 13 transposon mutants in orthologs |
| Comment | Hcp Secretion Island-I-encoded type VI secretion system (H1-T6SS) |
Cross-References
| RefSeq | YP_788251.1 |
| GI | 116053814 |
| Entrez | 4383512 |
| NCBI Locus Tag | PA14_01140 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Tse6
|
| Synonyms |
hypothetical protein |
| Evidence for Translation | |
| Charge (pH 7) | 7.14 |
| Kyte-Doolittle Hydrophobicity Value | 0.092 |
| Molecular Weight (kDa) | 45114.7 |
| Isoelectric Point (pI) | 9.44 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6OX6 | TRANSFERASE | 05/13/19 | Crystal structure of the complex between the Type VI effector Tas1 and its immunity protein | Pseudomonas aeruginosa | 2.17 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 23 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000092 (1670 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_01140
Search term: tse6
Search term: Tse6
|
Human Homologs
References
|
An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.
Whitney JC, Quentin D, Sawai S, LeRoux M, Harding BN, Ledvina HE, Tran BQ, Robinson H, Goo YA, Goodlett DR, Raunser S, Mougous JD
Cell 2015 Oct 22;163(3):607-19
PubMed ID: 26456113
|
|
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999
|