Pseudomonas aeruginosa PA7, PSPA7_0001 (dnaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0043565 sequence-specific DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00760
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006275 regulation of DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003688 DNA replication origin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006270 DNA replication initiation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PA7 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 308 335 1.8E-52
Pfam PF08299 Bacterial dnaA protein helix-turn-helix IPR013159 Chromosomal replication initiator, DnaA C-terminal 421 489 1.8E-31
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 178 388 2.17E-44
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 209 418 2.3E-7
Pfam PF11638 DnaA N-terminal domain IPR024633 DnaA N-terminal domain 1 61 8.8E-21
PANTHER PTHR30050 CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA - - 1 502 0.0
Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. IPR001957 Chromosomal replication control, initiator DnaA 1 511 34.175678
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 210 230 1.8E-52
NCBIfam TIGR00362 JCVI: chromosomal replication initiator protein DnaA IPR001957 Chromosomal replication control, initiator DnaA 4 510 0.0
CDD cd06571 Bac_DnaA_C IPR013159 Chromosomal replication initiator, DnaA C-terminal 421 510 9.05383E-42
Pfam PF00308 Bacterial dnaA protein IPR013317 Chromosomal replication initiator protein DnaA 177 394 1.0E-99
Gene3D G3DSA:1.10.8.60 - - - 343 413 6.2E-27
FunFam G3DSA:1.10.1750.10:FF:000001 Chromosomal replication initiator protein DnaA - - 419 512 1.4E-54
SMART SM00760 bac_dnaa_c7seqb IPR013159 Chromosomal replication initiator, DnaA C-terminal 420 489 9.1E-44
CDD cd00009 AAA - - 210 335 7.3178E-18
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 470 489 1.8E-52
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 176 342 1.2E-49
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 274 288 1.8E-52
Gene3D G3DSA:1.10.1750.10 - IPR010921 Trp repressor/replication initiator 419 512 4.0E-34
Gene3D G3DSA:3.30.300.180 - IPR038454 DnaA, N-terminal domain superfamily 1 100 1.5E-26
FunFam G3DSA:3.40.50.300:FF:000103 Chromosomal replication initiator protein DnaA - - 175 342 4.7E-100
SUPERFAMILY SSF48295 TrpR-like IPR010921 Trp repressor/replication initiator 408 510 6.28E-37
FunFam G3DSA:1.10.8.60:FF:000003 Chromosomal replication initiator protein DnaA - - 343 413 2.4E-33
PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature IPR020591 Chromosomal replication control, initiator DnaA-like 242 256 1.8E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.