Pseudomonas aeruginosa PAO1, PA0058 (dsbM)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0058
|
| Name |
dsbM
|
| Replicon | chromosome |
| Genomic location | 72680 - 73384 (+ strand) |
| Transposon Mutants | 1 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248748.1 |
| GI | 15595256 |
| Affymetrix | PA0058_at |
| DNASU | PaCD00006025 |
| Entrez | 880931 |
| GenBank | AAG03448.1 |
| INSDC | AAG03448.1 |
| NCBI Locus Tag | PA0058 |
| protein_id(GenBank) | gb|AAG03448.1|AE004445_9|gnl|PseudoCAP|PA0058 |
| TIGR | NTL03PA00059 |
| UniParc | UPI00000C4F0B |
| UniProtKB Acc | Q9I774 |
| UniProtKB ID | Q9I774_PSEAE |
| UniRef100 | UniRef100_Q9I774 |
| UniRef50 | UniRef50_V5UEA6 |
| UniRef90 | UniRef90_Z2DKX5 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DsbM
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -5.74 |
| Kyte-Doolittle Hydrophobicity Value | 0.003 |
| Molecular Weight (kDa) | 24.9 |
| Isoelectric Point (pI) | 5.29 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 5HFI | OXIDOREDUCTASE | 01/07/16 | Cytosolic disulfide reductase DsbM from Pseudomonas aeruginosa with GSH | Pseudomonas aeruginosa PAO1 | 1.801 | X-RAY DIFFRACTION | 100.0 |
| 5HFG | OXIDOREDUCTASE | 01/07/16 | Cytosolic disulfide reductase DsbM from Pseudomonas aeruginosa | Pseudomonas aeruginosa PAO1 | 1.823 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 83 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000057 (372 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0058
Search term: dsbM
Search term: DsbM
|
Human Homologs
References
|
DsbM, a novel disulfide oxidoreductase affects aminoglycoside resistance in Pseudomonas aeruginosa by OxyR-regulated response.
Wang X, Li M, Liu L, Mou R, Zhang X, Bai Y, Xu H, Qiao M
J. Microbiol. 2012 Dec;50(6):932-8
PubMed ID: 23274979
|