Pseudomonas aeruginosa PAO1, PA0094 (eagT6)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0094
|
| Name |
eagT6
|
| Replicon | chromosome |
| Genomic location | 114611 - 115045 (- strand) |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
| Comment | This protein is a molecular chaperone for the adjacently encoded T6SS effector Tse6 (PA0093) |
Cross-References
| RefSeq | NP_248784.1 |
| GI | 15595292 |
| Affymetrix | PA0094_at |
| DNASU | PaCD00006041 |
| Entrez | 879595 |
| GenBank | AAG03484.1 |
| INSDC | AAG03484.1 |
| NCBI Locus Tag | PA0094 |
| protein_id(GenBank) | gb|AAG03484.1|AE004448_3|gnl|PseudoCAP|PA0094 |
| TIGR | NTL03PA00095 |
| UniParc | UPI00000C4F2F |
| UniProtKB Acc | Q9I738 |
| UniProtKB ID | Q9I738_PSEAE |
| UniRef100 | UniRef100_W0YKR3 |
| UniRef50 | UniRef50_Q4K3M6 |
| UniRef90 | UniRef90_A6UXM9 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
EagT6
|
| Synonyms |
hypothetical protein |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -0.57 |
| Kyte-Doolittle Hydrophobicity Value | -0.464 |
| Molecular Weight (kDa) | 16.5 |
| Isoelectric Point (pI) | 6.80 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6XRF | CHAPERONE | 07/12/20 | EagT6 Tse6 NT complex | Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.56 | X-RAY DIFFRACTION | 100.0 |
| 1TU1 | STRUCTURAL GENOMICS, UNKNOWN FUNCTION | 06/24/04 | Crystal Structure of Protein of Unknown Function PA94 from Pseudomonas aeruginosa, Putative Regulator | Pseudomonas aeruginosa | 1.95 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000093 (314 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0094
Search term: eagT6
Search term: EagT6
|
Human Homologs
References
|
An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.
Whitney JC, Quentin D, Sawai S, LeRoux M, Harding BN, Ledvina HE, Tran BQ, Robinson H, Goo YA, Goodlett DR, Raunser S, Mougous JD
Cell 2015 Oct;163(3):607-19
PubMed ID: 26456113
|