Pseudomonas aeruginosa PAO1, PA0115

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0115
Name
Synonym: elaA
Replicon chromosome
Genomic location 135934 - 136386 (- strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248805.1
GI 15595313
Affymetrix PA0115_at
DNASU PaCD00006050
Entrez 880693
GenBank AAG03505.1
INSDC AAG03505.1
NCBI Locus Tag PA0115
protein_id(GenBank) gb|AAG03505.1|AE004449_14|gnl|PseudoCAP|PA0115
TIGR NTL03PA00116
UniParc UPI00000C4F44
UniProtKB Acc Q9I717
UniProtKB ID Q9I717_PSEAE
UniRef100 UniRef100_W0YKZ0
UniRef50 UniRef50_P0AEH3
UniRef90 UniRef90_A6UXQ1

Product

Feature Type CDS
Coding Frame 1
Product Name
Acyl-CoA N-acyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.15
Kyte-Doolittle Hydrophobicity Value -0.115
Molecular Weight (kDa) 17.1
Isoelectric Point (pI) 6.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1XEB TRANSFERASE 09/09/04 Crystal Structure of an Acyl-CoA N-acyltransferase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.35 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 262 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000113 (495 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0115

Human Homologs

References

Predicting drug targets by homology modelling of Pseudomonas aeruginosa proteins of unknown function.
Babic N, Kovacic F
PLoS One 2021;16(10):e0258385
PubMed ID: 34648550