Pseudomonas aeruginosa PAO1, PA0162 (opdC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0162
|
| Name |
opdC
Synonym: opdC |
| Replicon | chromosome |
| Genomic location | 184594 - 185928 (+ strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248852.1 |
| GI | 15595360 |
| Affymetrix | PA0162_at |
| Entrez | 879518 |
| GenBank | AAG03552.1 |
| INSDC | AAG03552.1 |
| NCBI Locus Tag | PA0162 |
| protein_id(GenBank) | gb|AAG03552.1|AE004454_4|gnl|PseudoCAP|PA0162 |
| TIGR | NTL03PA00163 |
| UniParc | UPI00000C4F71 |
| UniProtKB Acc | Q9I6X0 |
| UniProtKB ID | Q9I6X0_PSEAE |
| UniRef100 | UniRef100_Q9I6X0 |
| UniRef50 | UniRef50_V6A7C8 |
| UniRef90 | UniRef90_V6A7C8 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
histidine porin OpdC
|
| Synonyms |
histidine porin OpdC |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (48.86 kDa, PMID:21751344)
Detected by MALDI-TOF/TOF (PMID:19333994).
|
| Charge (pH 7) | -15.39 |
| Kyte-Doolittle Hydrophobicity Value | -0.488 |
| Molecular Weight (kDa) | 48.9 |
| Isoelectric Point (pI) | 4.79 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 3SY9 | MEMBRANE PROTEIN | 07/16/11 | Crystal structure of Pseudomonas aeruginosa OccD2 (OpdC) | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 99.8 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 24 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000160 (448 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0162
Search term: opdC
Search term: histidine porin OpdC
|
Human Homologs
References
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|