Pseudomonas aeruginosa PAO1, PA0473

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0473
Name
Synonym: psfA
Replicon chromosome
Genomic location 534196 - 534945 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249164.1
GI 15595670
Affymetrix PA0473_at
Entrez 878426
GenBank AAG03862.1
INSDC AAG03862.1
NCBI Locus Tag PA0473
protein_id(GenBank) gb|AAG03862.1|AE004485_3|gnl|PseudoCAP|PA0473
TIGR NTL03PA00474
UniParc UPI00000C5077
UniProtKB Acc Q9I645
UniProtKB ID Q9I645_PSEAE
UniRef100 UniRef100_Q9I645
UniRef50 UniRef50_Q9I645
UniRef90 UniRef90_Q9I645

Product

Feature Type CDS
Coding Frame 1
Product Name
probable glutathione S-transferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.40
Kyte-Doolittle Hydrophobicity Value -0.116
Molecular Weight (kDa) 28.3
Isoelectric Point (pI) 5.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 224 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000464 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0473

Human Homologs

Ensembl 110, assembly GRCh38.p14
glutathione S-transferase theta 4 [Source:HGNC Symbol;Acc:HGNC:26930]
E-value: 1.3e-05
Percent Identity: 25.0

References

Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4409-14
PubMed ID: 8633080