Pseudomonas aeruginosa PAO1, PA0506

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0506
Name
Replicon chromosome
Genomic location 564914 - 566719 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 12 transposon mutants in orthologs

Cross-References

RefSeq NP_249197.1
GI 15595703
Affymetrix PA0506_at
Entrez 878586
GenBank AAG03895.1
INSDC AAG03895.1
NCBI Locus Tag PA0506
protein_id(GenBank) gb|AAG03895.1|AE004487_9|gnl|PseudoCAP|PA0506
TIGR NTL03PA00507
UniParc UPI00000C5095
UniProtKB Acc Q9I612
UniProtKB ID Q9I612_PSEAE
UniRef100 UniRef100_W0YNA3
UniRef50 UniRef50_D6CM31
UniRef90 UniRef90_A0A098FYS7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acyl-CoA dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.92
Kyte-Doolittle Hydrophobicity Value -0.161
Molecular Weight (kDa) 65.4
Isoelectric Point (pI) 5.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 433 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000493 (2496 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0506

Human Homologs

References

Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994