Pseudomonas aeruginosa PAO1, PA0606 (agtD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0606
Name
agtD
Replicon chromosome
Genomic location 668461 - 669291 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249297.1
GI 15595803
Affymetrix PA0606_at
DNASU PaCD00006266
Entrez 880768
GenBank AAG03995.1
INSDC AAG03995.1
NCBI Locus Tag PA0606
protein_id(GenBank) gb|AAG03995.1|AE004497_2|gnl|PseudoCAP|PA0606
TIGR NTL03PA00607
UniParc UPI00000C50D6
UniProtKB Acc Q9I5T2
UniProtKB ID Q9I5T2_PSEAE
UniRef100 UniRef100_A0A069QIR4
UniRef50 UniRef50_D8NJ10
UniRef90 UniRef90_A4XZI1

Product

Feature Type CDS
Coding Frame 1
Product Name
AgtD
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.19
Kyte-Doolittle Hydrophobicity Value 0.959
Molecular Weight (kDa) 29.8
Isoelectric Point (pI) 9.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 553 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000589 (513 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0606
Search term: agtD
Search term: AgtD

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1.
Chou HT, Li JY, Lu CD
Curr Microbiol 2014 Jan;68(1):59-63
PubMed ID: 23982201