Pseudomonas aeruginosa PAO1, PA0612 (ptrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0612
Name
ptrB
Synonym: ptrB
Replicon chromosome
Genomic location 674419 - 674619 (+ strand)
CommentExpression of ptrB is repressed by prtR (PA0611). PrtR mediated repression of ptrB is relieved by stresses such as DNA damage.

Cross-References

RefSeq NP_249303.1
GI 15595809
Affymetrix PA0612_i_at
DNASU PaCD00006269
Entrez 878190
GenBank AAG04001.1
INSDC AAG04001.1
NCBI Locus Tag PA0612
protein_id(GenBank) gb|AAG04001.1|AE004497_8|gnl|PseudoCAP|PA0612
TIGR NTL03PA00613
UniParc UPI00000D4290
UniProtKB Acc G3XDA6
UniProtKB ID G3XDA6_PSEAE
UniRef100 UniRef100_W0YM29
UniRef50 UniRef50_W0YM29
UniRef90 UniRef90_W0YM29

Product

Feature Type CDS
Coding Frame 1
Product Name
repressor, PtrB
Product Name Confidence: Class 1
Synonyms New product name: repressor, PtrB
Evidence for Translation
Charge (pH 7) -2.68
Kyte-Doolittle Hydrophobicity Value -0.550
Molecular Weight (kDa) 7.3
Isoelectric Point (pI) 5.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 60 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000595 (669 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0612
Search term: ptrB
Search term: repressor, PtrB

Human Homologs

References

PtrB of Pseudomonas aeruginosa suppresses the type III secretion system under the stress of DNA damage.
Wu W, Jin S
J Bacteriol 2005 Sep;187(17):6058-68
PubMed ID: 16109947