Pseudomonas aeruginosa PAO1, PA0950

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0950
Name
Replicon chromosome
Genomic location 1037172 - 1037525 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249641.1
GI 15596147
Affymetrix PA0950_at
DNASU PaCD00006437
Entrez 881999
GenBank AAG04339.1
INSDC AAG04339.1
NCBI Locus Tag PA0950
protein_id(GenBank) gb|AAG04339.1|AE004529_5|gnl|PseudoCAP|PA0950
TIGR NTL03PA00951
UniParc UPI00000C51D6
UniProtKB Acc Q9I508
UniProtKB ID Q9I508_PSEAE
UniRef100 UniRef100_W0YLK2
UniRef50 UniRef50_Q02IB1
UniRef90 UniRef90_Q02IB1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable arsenate reductase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.56
Kyte-Doolittle Hydrophobicity Value -0.042
Molecular Weight (kDa) 12.8
Isoelectric Point (pI) 6.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 301 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000916 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0950

Human Homologs

References

Nucleotide sequence of the structural genes for an anion pump. The plasmid-encoded arsenical resistance operon.
Chen CM, Misra TK, Silver S, Rosen BP
J Biol Chem 1986 Nov 15;261(32):15030-8
PubMed ID: 3021763
The plasmid-encoded arsenical resistance pump: an anion-translocating ATPase.
Rosen BP
Res Microbiol 1990 Mar-Apr;141(3):336-41
PubMed ID: 1704144
The arsenical resistance operon of IncN plasmid R46.
Bruhn DF, Li J, Silver S, Roberto F, Rosen BP
FEMS Microbiol Lett 1996 Jun 1;139(2-3):149-53
PubMed ID: 8674982