Pseudomonas aeruginosa PAO1, PA1104 (fliI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1104
Name
fliI
Replicon chromosome
Genomic location 1196021 - 1197376 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249795.1
GI 15596301
Affymetrix PA1104_fliI_at
Entrez 882010
GenBank AAG04493.1
INSDC AAG04493.1
NCBI Locus Tag PA1104
protein_id(GenBank) gb|AAG04493.1|AE004540_13|gnl|PseudoCAP|PA1104
TIGR NTL03PA01105
UniParc UPI00000C524B
UniProtKB Acc Q9I4N1
UniProtKB ID FLII_PSEAE
UniRef100 UniRef100_Q9I4N1
UniRef50 UniRef50_Q9I4N1
UniRef90 UniRef90_Q9I4N1

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellum-specific ATP synthase FliI
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.84
Kyte-Doolittle Hydrophobicity Value -0.087
Molecular Weight (kDa) 48.6
Isoelectric Point (pI) 6.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001065 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1104
Search term: fliI

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]
E-value: 1.4e-32
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]
E-value: 1.4e-32
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
ATP synthase F1 subunit alpha [Source:HGNC Symbol;Acc:HGNC:823]
E-value: 1.4e-32
Percent Identity: 28.0

References

Genetic and biochemical analysis of Salmonella typhimurium FliI, a flagellar protein related to the catalytic subunit of the F0F1 ATPase and to virulence proteins of mammalian and plant pathogens.
Dreyfus G, Williams AW, Kawagishi I, Macnab RM
J Bacteriol 1993 May;175(10):3131-8
PubMed ID: 8491729
A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.
Itoh T, Aiba H, Baba T, Hayashi K, Inada T, Isono K, Kasai H, Kimura S, Kitakawa M, Kitagawa M, Makino K, Miki T, Mizobuchi K, Mori H, Mori T, Motomura K, Nakade S, Nakamura Y, Nashimoto H, Nishio Y, Oshima T, Saito N, Sampei G, Seki Y, Horiuchi T
DNA Res 1996 Dec 31;3(6):379-92
PubMed ID: 9097040