Pseudomonas aeruginosa PAO1, PA1240

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA1240
Name
Replicon	chromosome
Genomic location	1341851 - 1342648 (- strand)
Transposon Mutants	1 transposon mutants in PAO1
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_249931.1
GI	15596437
Affymetrix	PA1240_at
Entrez	881179
GenBank	AAG04629.1
INSDC	AAG04629.1
NCBI Locus Tag	PA1240
protein_id(GenBank)	gb|AAG04629.1|AE004553_6|gnl|PseudoCAP|PA1240
TIGR	NTL03PA01241
UniParc	UPI00000C52C9
UniProtKB Acc	Q9I498
UniProtKB ID	Q9I498_PSEAE
UniRef100	UniRef100_S0HYR9
UniRef50	UniRef50_A5CQ24
UniRef90	UniRef90_S0HYR9

Product

Feature Type	CDS
Coding Frame	1
Product Name	probable enoyl-CoA hydratase/isomerase Product Name Confidence: Class 3
Synonyms
Evidence for Translation	Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7)	-4.09
Kyte-Doolittle Hydrophobicity Value	-0.115
Molecular Weight (kDa)	28.6
Isoelectric Point (pI)	5.46

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3LAO	lyase, isomerase	01/06/10	Crystal Structure of Enoyl-CoA Hydratase from Pseudomonas aeruginosa PA01	Pseudomonas aeruginosa	2.4	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 440 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001192 (163 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA1240 Search term: probable enoyl-CoA hydratase/isomerase

Human Homologs

References

A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map. Aiba H, Baba T, Hayashi K, Inada T, Isono K, Itoh T, Kasai H, Kashimoto K, Kimura S, Kitakawa M, Kitagawa M, Makino K, Miki T, Mizobuchi K, Mori H, Mori T, Motomura K, Nakade S, Nakamura Y, Nashimoto H, Nishio Y, Oshima T, Saito N, Sampei G, Horiuchi T DNA Res 1996 Dec 31;3(6):363-77 PubMed ID: 9097039