Pseudomonas aeruginosa PAO1, PA1317 (cyoA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1317
Name
cyoA
Replicon chromosome
Genomic location 1428080 - 1429075 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250008.1
GI 15596514
Affymetrix PA1317_cyoA_at
DNASU PaCD00006608
Entrez 881513
GenBank AAG04706.1
INSDC AAG04706.1
NCBI Locus Tag PA1317
protein_id(GenBank) gb|AAG04706.1|AE004561_2|gnl|PseudoCAP|PA1317
TIGR NTL03PA01318
UniParc UPI00000C530C
UniProtKB Acc Q9I427
UniProtKB ID CYOA_PSEAE
UniRef100 UniRef100_Q9I427
UniRef50 UniRef50_P0ABJ2
UniRef90 UniRef90_Q9I427

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome o ubiquinol oxidase subunit II
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.18
Kyte-Doolittle Hydrophobicity Value -0.020
Molecular Weight (kDa) 36.6
Isoelectric Point (pI) 5.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 279 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001258 (502 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1317
Search term: cyoA

Human Homologs

References

The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases.
Chepuri V, Lemieux L, Au DC, Gennis RB
J Biol Chem 1990 Jul 5;265(19):11185-92
PubMed ID: 2162835
Recent studies of the cytochrome o terminal oxidase complex of Escherichia coli.
Chepuri V, Lemieux L, Hill J, Alben JO, Gennis RB
Biochim Biophys Acta 1990 Jul 25;1018(2-3):124-7
PubMed ID: 2168206