Pseudomonas aeruginosa PAO1, PA1340 (aatM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1340
Name
aatM
Replicon chromosome
Genomic location 1454201 - 1454869 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250031.1
GI 15596537
Affymetrix PA1340_at
DNASU PaCD00006618
Entrez 882230
GenBank AAG04729.1
INSDC AAG04729.1
NCBI Locus Tag PA1340
protein_id(GenBank) gb|AAG04729.1|AE004563_6|gnl|PseudoCAP|PA1340
TIGR NTL03PA01341
UniParc UPI00000C5323
UniProtKB Acc Q9I404
UniProtKB ID Q9I404_PSEAE
UniRef100 UniRef100_Q9I404
UniRef50 UniRef50_P0AER7
UniRef90 UniRef90_Q9I404

Product

Feature Type CDS
Coding Frame 1
Product Name
AatM
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.16
Kyte-Doolittle Hydrophobicity Value 0.784
Molecular Weight (kDa) 24.6
Isoelectric Point (pI) 9.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 447 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001275 (1254 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1340
Search term: aatM
Search term: AatM

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.
Oshima T, Aiba H, Baba T, Fujita K, Hayashi K, Honjo A, Ikemoto K, Inada T, Itoh T, Kajihara M, Kanai K, Kashimoto K, Kimura S, Kitagawa M, Makino K, Masuda S, Miki T, Mizobuchi K, Mori H, Motomura K, Nakamura Y, Nashimoto H, Nishio Y, Saito N, Horiuchi T
DNA Res 1996 Jun 30;3(3):137-55
PubMed ID: 8905232
Characterization of a Pseudomonas putida ABC transporter (AatJMQP) required for acidic amino acid uptake: biochemical properties and regulation by the Aau two-component system.
Singh B, Röhm KH
Microbiology (Reading) 2008 Mar;154(Pt 3):797-809
PubMed ID: 18310026