Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1432
|
Name |
lasI
|
Replicon | chromosome |
Genomic location | 1559254 - 1559859 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250123.1 |
GI | 15596629 |
Affymetrix | PA1432_lasI_at |
DNASU | PaCD00006659 |
Entrez | 881777 |
GenBank | AAG04821.1 |
INSDC | AAG04821.1 |
NCBI Locus Tag | PA1432 |
protein_id(GenBank) | gb|AAG04821.1|AE004572_9|gnl|PseudoCAP|PA1432 |
TIGR | NTL03PA01433 |
UniParc | UPI000012E230 |
UniProtKB Acc | P33883 |
UniProtKB ID | LASI_PSEAE |
UniRef100 | UniRef100_P33883 |
UniRef50 | UniRef50_P33883 |
UniRef90 | UniRef90_P33883 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
autoinducer synthesis protein LasI
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -1.13 |
Kyte-Doolittle Hydrophobicity Value | -0.104 |
Molecular Weight (kDa) | 22.7 |
Isoelectric Point (pI) | 6.52 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1RO5 | SIGNALING PROTEIN | 12/01/03 | Crystal Structure of the AHL Synthase LasI | Pseudomonas aeruginosa | 2.3 | X-RAY DIFFRACTION | 98.0 |
Source 1 | |
Database | VFDB : VF0093 |
Category | N-(3-oxo-dodecanoyl)-L-homoserine lactone QS system |
Evidence |
|
Host Organism | |
Notes | |
Reference |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 58 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001349 (304 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1432
Search term: lasI
Search term: autoinducer synthesis protein LasI
|
Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication.
Passador L, Cook JM, Gambello MJ, Rust L, Iglewski BH
Science 1993 May 21;260(5111):1127-30
PubMed ID: 8493556
|
Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.
Pearson JP, Gray KM, Passador L, Tucker KD, Eberhard A, Iglewski BH, Greenberg EP
Proc Natl Acad Sci U S A 1994 Jan 4;91(1):197-201
PubMed ID: 8278364
|