Pseudomonas aeruginosa UCBPP-PA14, PA14_01830

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_01830
Name
Replicon chromosome
Genomic location 167065 - 168015 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs

Cross-References

RefSeq YP_788306.1
GI 116053869
EC Number 3.5.4.4
Entrez 4383548
INSDC ABJ15105.1
NCBI Locus Tag PA14_01830
UniParc UPI0000396C5C
UniProtKB Acc Q02UT0
UniProtKB ID ADE_PSEAB
UniRef100 UniRef100_Q02UT0
UniRef50 UniRef50_A6UXT7
UniRef90 UniRef90_A6UXT7

Product

Feature Type CDS
Coding Frame 1
Product Name
adenosine deaminase
Synonyms
Evidence for Translation
Charge (pH 7) -15.43
Kyte-Doolittle Hydrophobicity Value -0.272
Molecular Weight (kDa) 36.1
Isoelectric Point (pI) 4.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3OU8 HYDROLASE 09/14/10 The crystal structure of adenosine deaminase from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.51 X-RAY DIFFRACTION 99.4
3PAO HYDROLASE 10/19/10 The crystal structure of adenosine deaminase with adenine bound from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.493 X-RAY DIFFRACTION 99.4
3PAN HYDROLASE 10/19/10 The crystal structure of adenosine deaminase with hypoxanthine bound from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.627 X-RAY DIFFRACTION 99.4
3PBM HYDROLASE 10/20/10 The crystal structure of adenosine deaminase in complex with chloropurine from Pseudomonas aeruginosa Pseudomonas aeruginosa 2.591 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 254 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000146 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01830

Human Homologs

Ensembl 110, assembly GRCh38.p14
adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186]
E-value: 5.8e-22
Percent Identity: 23.9

References

No references are associated with this feature.