Pseudomonas aeruginosa UCBPP-PA14, PA14_01830

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_01830
Name
Replicon	chromosome
Genomic location	167065 - 168015 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	6 transposon mutants in orthologs

Cross-References

RefSeq	YP_788306.1
GI	116053869
EC Number	3.5.4.4
Entrez	4383548
INSDC	ABJ15105.1
NCBI Locus Tag	PA14_01830
UniParc	UPI0000396C5C
UniProtKB Acc	Q02UT0
UniProtKB ID	ADE_PSEAB
UniRef100	UniRef100_Q02UT0
UniRef50	UniRef50_A6UXT7
UniRef90	UniRef90_A6UXT7

Product

Feature Type	CDS
Coding Frame	1
Product Name	adenosine deaminase
Synonyms
Evidence for Translation
Charge (pH 7)	-15.43
Kyte-Doolittle Hydrophobicity Value	-0.272
Molecular Weight (kDa)	36.1
Isoelectric Point (pI)	4.80

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
3PAN	HYDROLASE	10/19/10	The crystal structure of adenosine deaminase with hypoxanthine bound from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.627	X-RAY DIFFRACTION	99.4
3PAO	HYDROLASE	10/19/10	The crystal structure of adenosine deaminase with adenine bound from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.493	X-RAY DIFFRACTION	99.4
3PBM	HYDROLASE	10/20/10	The crystal structure of adenosine deaminase in complex with chloropurine from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.591	X-RAY DIFFRACTION	99.4
3OU8	HYDROLASE	09/14/10	The crystal structure of adenosine deaminase from Pseudomonas aeruginosa	Pseudomonas aeruginosa	2.51	X-RAY DIFFRACTION	99.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 254 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000146 (532 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_01830 Search term: adenosine deaminase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000441818 adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186] E-value: 5.8e-22 Percent Identity: 23.9

References