Pseudomonas aeruginosa UCBPP-PA14, PA14_08360 (trpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_08360
Name
trpC
Replicon chromosome
Genomic location 716114 - 716950 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_788821.1
GI 116054376
EC Number 4.1.1.48
Entrez 4383976
INSDC ABJ15612.1
NCBI Locus Tag PA14_08360
UniParc UPI0000396E23
UniProtKB Acc Q02TB5
UniProtKB ID TRPC_PSEAB
UniRef100 UniRef100_Q02TB5
UniRef50 UniRef50_P00911
UniRef90 UniRef90_P20577

Product

Feature Type CDS
Coding Frame 1
Product Name
indole-3-glycerol-phosphate synthase
Synonyms
Evidence for Translation
Charge (pH 7) -11.35
Kyte-Doolittle Hydrophobicity Value 0.095
Molecular Weight (kDa) 30.3
Isoelectric Point (pI) 4.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6Y88 LYASE 03/03/20 IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP Pseudomonas aeruginosa 2.09983 X-RAY DIFFRACTION 99.3

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000631 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_08360
Search term: trpC

Human Homologs

References

No references are associated with this feature.