Pseudomonas aeruginosa UCBPP-PA14, PA14_09150 (katA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_09150
Name
katA
Replicon chromosome
Genomic location 773110 - 774558 (+ strand)
Transposon Mutants 3 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq YP_788883.1
GI 116052272
Entrez 4382943
INSDC ABJ13508.1
NCBI Locus Tag PA14_09150
UniParc UPI0000127076
UniProtKB Acc Q02T53
UniProtKB ID Q02T53_PSEAB
UniRef100 UniRef100_O52762
UniRef50 UniRef50_P42321
UniRef90 UniRef90_O52762

Product

Feature Type CDS
Coding Frame 1
Product Name
catalase
Synonyms
Evidence for Translation
Charge (pH 7) -3.20
Kyte-Doolittle Hydrophobicity Value -0.655
Molecular Weight (kDa) 55.6
Isoelectric Point (pI) 6.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4E37 OXIDOREDUCTASE 03/09/12 Crystal Structure of P. aeruginosa catalase, KatA tetramer Pseudomonas aeruginosa 2.53 X-RAY DIFFRACTION 100.0

Virulence Evidence

Source 1
Database Victors : 4417
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Drosophila melanogaster
Notes
Reference 15972537
Source 2
Database Victors : 4417
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Mus musculus
Notes
Reference 15972537

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 315 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001474 (1465 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_09150
Search term: katA
Search term: catalase

Human Homologs

Ensembl 110, assembly GRCh38.p14
catalase [Source:HGNC Symbol;Acc:HGNC:1516]
E-value: 2.9e-142
Percent Identity: 52.0

References

No references are associated with this feature.