Pseudomonas aeruginosa UCBPP-PA14, PA14_09520 (mexI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_09520
Name
mexI
Replicon chromosome
Genomic location 816306 - 819395 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 11 transposon mutants in orthologs

Cross-References

RefSeq YP_788912.1
GI 116052244
Entrez 4382217
INSDC ABJ13480.1
NCBI Locus Tag PA14_09520
UniParc UPI00003962ED
UniProtKB Acc Q02T24
UniProtKB ID Q02T24_PSEAB
UniRef100 UniRef100_W0YY82
UniRef50 UniRef50_W0YY82
UniRef90 UniRef90_W0YY82

Product

Feature Type CDS
Coding Frame 1
Product Name
RND efflux transporter
Synonyms
Evidence for Translation
Charge (pH 7) -6.64
Kyte-Doolittle Hydrophobicity Value 0.352
Molecular Weight (kDa) 111.1
Isoelectric Point (pI) 5.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexI MexI is the inner membrane transporter of the efflux complex MexGHI-OpmD. [PMID:15817779, PMID:12917802] ARO:3000808 protein homolog model Strict 1910.6 99.9 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001500 (799 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_09520
Search term: mexI

Human Homologs

References

No references are associated with this feature.