Pseudomonas aeruginosa UCBPP-PA14, PA14_39890 (phzF2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_39890
Name
phzF2
Replicon chromosome
Genomic location 3556129 - 3556965 (- strand)
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_791335.1
GI 116049856
Entrez 4385622
NCBI Locus Tag PA14_39890

Product

Feature Type CDS
Coding Frame 1
Product Name
phenazine biosynthesis protein
Synonyms
Evidence for Translation
Charge (pH 7) -2.96
Kyte-Doolittle Hydrophobicity Value -0.108
Molecular Weight (kDa) 30.3
Isoelectric Point (pI) 6.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database PseudoCAP
Category Phenazine biosynthesis
Evidence ECO:0000316
genetic interaction evidence used in manual assertion
Host Organism Mus musculus
Notes phz2 operon, but not phz1 operon required for lung colonization in acute mouse pulmonary Infection model
Infection model acute mouse pulmonary Infection model
Reference 23129634

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 330 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001492 (429 members)
Putative Inparalogs 1 predicted inparalogs
phenazine biosynthesis protein (PA14_09420) 100.0% identity

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_39890
Search term: phzF2

Human Homologs

Ensembl 110, assembly GRCh38.p14
phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]
E-value: 1.2e-10
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]
E-value: 1.2e-10
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
phenazine biosynthesis like protein domain containing [Source:HGNC Symbol;Acc:HGNC:23301]
E-value: 1.2e-10
Percent Identity: 28.0

References

No references are associated with this feature.