Pseudomonas aeruginosa UCBPP-PA14, PA14_45890

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_45890
Name
Replicon chromosome
Genomic location 4077152 - 4080262 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq YP_791816.1
GI 116049381
Entrez 4382870
INSDC ABJ10617.1
NCBI Locus Tag PA14_45890
UniParc UPI0000396717
UniProtKB Acc Q02JS0
UniProtKB ID Q02JS0_PSEAB
UniRef100 UniRef100_W1ML50
UniRef50 UniRef50_A0A085UAG0
UniRef90 UniRef90_B7UWB6

Product

Feature Type CDS
Coding Frame 1
Product Name
RND efflux transporter
Synonyms
Evidence for Translation
Charge (pH 7) -7.38
Kyte-Doolittle Hydrophobicity Value 0.445
Molecular Weight (kDa) 110.8
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
mexN MexN is the inner membrane transporter of the MexMN-OprM multidrug efflux complex. [PMID:19713238] ARO:3003705 protein homolog model Strict 1913.7 99.81 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001353 (1523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_45890

Human Homologs

References

No references are associated with this feature.