Pseudomonas aeruginosa UCBPP-PA14, PA14_51410 (pqsC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_51410
Name
pqsC
Replicon chromosome
Genomic location 4568032 - 4569078 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792273.1
GI 116048926
Entrez 4379982
INSDC ABJ10162.1
NCBI Locus Tag PA14_51410
UniParc UPI00000C51FA
UniProtKB Acc Q02IG3
UniProtKB ID Q02IG3_PSEAB
UniRef100 UniRef100_W0YN16
UniRef50 UniRef50_W0YN16
UniRef90 UniRef90_W0YN16

Product

Feature Type CDS
Coding Frame 1
Product Name
PqsC
Synonyms
Evidence for Translation
Charge (pH 7) -7.49
Kyte-Doolittle Hydrophobicity Value -0.050
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 4.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6ET3 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) Pseudomonas aeruginosa PAO1 2.25 X-RAY DIFFRACTION 99.7
6ET1 TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 2) Pseudomonas aeruginosa PAO1 2.65 X-RAY DIFFRACTION 100.0
6ET2 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 3) Pseudomonas aeruginosa PAO1 2.6 X-RAY DIFFRACTION 99.7
5DWZ TRANSFERASE 09/23/15 Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal Pseudomonas aeruginosa 2.04 X-RAY DIFFRACTION 99.7
6ESZ TRANSFERASE 10/25/17 Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 1) Pseudomonas aeruginosa PAO1 1.84 X-RAY DIFFRACTION 100.0
6ET0 TRANSFERASE 10/25/17 Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) Pseudomonas aeruginosa PAO1 1.53 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 539 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000961 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51410
Search term: pqsC
Search term: PqsC

Human Homologs

References

No references are associated with this feature.