Pseudomonas aeruginosa UCBPP-PA14, PA14_55410 (lapC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_55410
Name
lapC
Replicon chromosome
Genomic location 4930632 - 4931810 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792606.1
GI 116048595
Entrez 4382535
INSDC ABJ09831.1
NCBI Locus Tag PA14_55410
UniParc UPI000045D005
UniProtKB Acc Q02HI0
UniProtKB ID PPBL_PSEAB
UniRef100 UniRef100_Q02HI0
UniRef50 UniRef50_P85173
UniRef90 UniRef90_K4LAH1

Product

Feature Type CDS
Coding Frame 1
Product Name
LapC
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 7.06
Kyte-Doolittle Hydrophobicity Value -0.036
Molecular Weight (kDa) 40.7
Isoelectric Point (pI) 9.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
sodium dodecyl sulfate polyacrylamide gel electrophoresis evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 119 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000667 (394 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_55410
Search term: lapC
Search term: LapC

Human Homologs

References

Type II-dependent secretion of a Pseudomonas aeruginosa DING protein.
Ball G, Viarre V, Garvis S, Voulhoux R, Filloux A
Res Microbiol 2012 Jul;163(6-7):457-69
PubMed ID: 22835944