Pseudomonas aeruginosa PAO1, PA4017

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4017
Name
Synonym: yraR
Replicon chromosome
Genomic location 4496912 - 4497553 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252706.1
GI 15599212
Affymetrix PA4017_at
DNASU PaCD00007754
Entrez 878987
GenBank AAG07404.1
INSDC AAG07404.1
NCBI Locus Tag PA4017
protein_id(GenBank) gb|AAG07404.1|AE004818_10|gnl|PseudoCAP|PA4017
TIGR NTL03PA04017
UniParc UPI00000C5BC3
UniProtKB Acc Q9HX10
UniProtKB ID Q9HX10_PSEAE
UniRef100 UniRef100_W0YXH7
UniRef50 UniRef50_G8PY10
UniRef90 UniRef90_W0YXH7

Product

Feature Type CDS
Coding Frame 1
Product Name
thioesterase
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.11
Kyte-Doolittle Hydrophobicity Value -0.029
Molecular Weight (kDa) 23.2
Isoelectric Point (pI) 7.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2A35 STRUCTURAL GENOMICS, UNKNOWN FUNCTION 06/23/05 1.5 A Crystal Structure of a Protein of Unknown Function PA4017 from Pseudomonas aeruginosa PAO1, Possible Epimerase Pseudomonas aeruginosa 1.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001666 (527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4017
Search term: thioesterase

Human Homologs

References

Towards fully automated structure-based function prediction in structural genomics: a case study.
Watson JD, Sanderson S, Ezersky A, Savchenko A, Edwards A, Orengo C, Joachimiak A, Laskowski RA, Thornton JM
J Mol Biol 2007 Apr 13;367(5):1511-22
PubMed ID: 17316683