Pseudomonas aeruginosa PAO1, PA4036

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4036
Name
Replicon chromosome
Genomic location 4516570 - 4518870 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252725.1
GI 15599231
Affymetrix PA4036_at
Entrez 879031
GenBank AAG07423.1
INSDC AAG07423.1
NCBI Locus Tag PA4036
protein_id(GenBank) gb|AAG07423.1|AE004820_8|gnl|PseudoCAP|PA4036
TIGR NTL03PA04036
UniParc UPI00000C5BD3
UniProtKB Acc Q9HWZ1
UniProtKB ID Q9HWZ1_PSEAE
UniRef100 UniRef100_W0YZC1
UniRef50 UniRef50_Q4KKS1
UniRef90 UniRef90_Q02SK3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component sensor
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -6.00
Kyte-Doolittle Hydrophobicity Value 0.002
Molecular Weight (kDa) 84.1
Isoelectric Point (pI) 5.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 616 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001648 (378 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4036

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Phosphate regulon in members of the family Enterobacteriaceae: comparison of the phoB-phoR operons of Escherichia coli, Shigella dysenteriae, and Klebsiella pneumoniae.
Lee TY, Makino K, Shinagawa H, Amemura M, Nakata A
J Bacteriol 1989 Dec;171(12):6593-9
PubMed ID: 2556368