Pseudomonas aeruginosa PAO1, PA4096

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4096
Name
Synonym: phlE
Replicon chromosome
Genomic location 4578254 - 4579513 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252785.1
GI 15599291
Affymetrix PA4096_at
Entrez 878702
GenBank AAG07483.1
INSDC AAG07483.1
NCBI Locus Tag PA4096
protein_id(GenBank) gb|AAG07483.1|AE004826_1|gnl|PseudoCAP|PA4096
TIGR NTL03PA04096
UniParc UPI00000C5C0A
UniProtKB Acc Q9HWT2
UniProtKB ID Q9HWT2_PSEAE
UniRef100 UniRef100_U8NP84
UniRef50 UniRef50_J2FBG9
UniRef90 UniRef90_B7V7A8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 13.92
Kyte-Doolittle Hydrophobicity Value 0.826
Molecular Weight (kDa) 44.6
Isoelectric Point (pI) 10.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 466 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001592 (326 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4096

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2,4-diacetylphloroglucinol from Pseudomonas fluorescens Q2-87.
Bangera MG, Thomashow LS
J Bacteriol 1999 May;181(10):3155-63
PubMed ID: 10322017