Pseudomonas aeruginosa PAO1, PA4179

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4179
Name
Synonym: opdN
Replicon chromosome
Genomic location 4674944 - 4676239 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252868.1
GI 15599374
Affymetrix PA4179_at
Entrez 880312
GenBank AAG07566.1
INSDC AAG07566.1
NCBI Locus Tag PA4179
protein_id(GenBank) gb|AAG07566.1|AE004834_6|gnl|PseudoCAP|PA4179
TIGR NTL03PA04179
UniParc UPI00000C5C58
UniProtKB Acc Q9HWK2
UniProtKB ID Q9HWK2_PSEAE
UniRef100 UniRef100_X7DV62
UniRef50 UniRef50_Q4KGR5
UniRef90 UniRef90_B7V6C7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable porin
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.11
Kyte-Doolittle Hydrophobicity Value -0.489
Molecular Weight (kDa) 47.8
Isoelectric Point (pI) 9.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4FSO TRANSPORT PROTEIN 06/27/12 Crystal Structure of Pseudomonas aeruginosa OccK10 (OpdN) Pseudomonas aeruginosa 2.75 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 19 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000729 (839 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4179
Search term: probable porin

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295