Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4217
|
Name |
phzS
|
Replicon | chromosome |
Genomic location | 4720301 - 4721509 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_252907.1 |
GI | 15599413 |
Affymetrix | PA4217_at |
Entrez | 881836 |
GenBank | AAG07605.1 |
INSDC | AAG07605.1 |
NCBI Locus Tag | PA4217 |
protein_id(GenBank) | gb|AAG07605.1|AE004838_9|gnl|PseudoCAP|PA4217 |
TIGR | NTL03PA04218 |
UniParc | UPI00000C5C77 |
UniProtKB Acc | Q9HWG9 |
UniProtKB ID | Q9HWG9_PSEAE |
UniRef100 | UniRef100_Q9HWG9 |
UniRef50 | UniRef50_Q9HWG9 |
UniRef90 | UniRef90_Q9HWG9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
flavin-containing monooxygenase
|
Synonyms |
probable FAD-dependent monooxygenase |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -7.16 |
Kyte-Doolittle Hydrophobicity Value | -0.182 |
Molecular Weight (kDa) | 43.6 |
Isoelectric Point (pI) | 5.94 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3C96 | OXIDOREDUCTASE | 02/15/08 | Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240 | Pseudomonas aeruginosa PAO1 | 1.9 | X-RAY DIFFRACTION | 100.0 |
2RGJ | OXIDOREDUCTASE | 10/03/07 | Crystal structure of flavin-containing monooxygenase PhzS | Pseudomonas aeruginosa | 2.4 | X-RAY DIFFRACTION | 100.0 |
Source 1 | |
Database | VFDB : VF0100 |
Category | Phenazine biosynthesis |
Evidence |
|
Host Organism | |
Notes | |
Reference | |
Source 2 | |
Database | Victors : 4259 |
Category | Phenazine biosynthesis |
Evidence |
ECO:0000015
mutant phenotype evidence
|
Host Organism | Mus musculus |
Notes | |
Reference | 15213173 |
Source 3 | |
Database | PseudoCAP |
Category | Phenazine biosynthesis |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | |
Infection model | acute pulmonary Infection model |
Infection model | chronic pulmonary Infection model |
Reference | 15213173 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 221 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001490 (1026 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4217
Search term: phzS
Search term: flavin-containing monooxygenase
|
Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.
Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS
J Bacteriol 2001 Nov;183(21):6454-65
PubMed ID: 11591691
|