Pseudomonas aeruginosa PAO1, PA4233

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4233
Name
Synonym: yajR
Replicon chromosome
Genomic location 4747154 - 4748542 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252923.1
GI 15599429
Affymetrix PA4233_at
Entrez 881826
GenBank AAG07621.1
INSDC AAG07621.1
NCBI Locus Tag PA4233
protein_id(GenBank) gb|AAG07621.1|AE004840_7|gnl|PseudoCAP|PA4233
TIGR NTL03PA04234
UniParc UPI00000C5C7D
UniProtKB Acc Q9HWG1
UniProtKB ID Q9HWG1_PSEAE
UniRef100 UniRef100_W0Z002
UniRef50 UniRef50_A0A024HC03
UniRef90 UniRef90_A6UZL8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (48.82 kDa, PMID:21751344)
Charge (pH 7) 8.03
Kyte-Doolittle Hydrophobicity Value 0.800
Molecular Weight (kDa) 48.8
Isoelectric Point (pI) 9.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 517 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001477 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4233

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344