Pseudomonas aeruginosa PAO1, PA4271 (rplL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4271
Name
rplL
Replicon chromosome
Genomic location 4780839 - 4781207 (- strand)

Cross-References

RefSeq NP_252961.1
GI 15599467
Affymetrix PA4271_rplL_at
DNASU PaCD00007853
Entrez 881701
GenBank AAG07659.1
INSDC AAG07659.1
NCBI Locus Tag PA4271
protein_id(GenBank) gb|AAG07659.1|AE004843_1|gnl|PseudoCAP|PA4271
TIGR NTL03PA04272
UniParc UPI00001341BC
UniProtKB Acc Q9HWC8
UniProtKB ID RL7_PSEAE
UniRef100 UniRef100_A6UZI0
UniRef50 UniRef50_Q31IZ0
UniRef90 UniRef90_C1DKK4

Product

Feature Type CDS
Coding Frame 1
Product Name
50S ribosomal protein L7 / L12
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.00
Kyte-Doolittle Hydrophobicity Value 0.183
Molecular Weight (kDa) 12.5
Isoelectric Point (pI) 4.39

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 592 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001440 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4271
Search term: rplL

Human Homologs

References

Nucleotide sequence of the ribosomal protein gene cluster adjacent to the gene for RNA polymerase subunit beta in Escherichia coli.
Post LE, Strycharz GD, Nomura M, Lewis H, Dennis PP
Proc Natl Acad Sci U S A 1979 Apr;76(4):1697-701
PubMed ID: 377281
[Nucleotide sequence of the rplL gene coding for ribosomal protein L7/L12 of Pseudomonas putida].
Borodin AM, Danilkovich AV, Allikmets RL
Bioorg Khim 1989 Apr;15(4):560-1
PubMed ID: 2751714
Topology of the secondary structure elements of ribosomal protein L7/L12 from E. coli in solution.
Bocharov EV, Gudkov AT, Arseniev AS
FEBS Lett 1996 Feb 5;379(3):291-4
PubMed ID: 8603708
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142