Pseudomonas aeruginosa PAO1, PA5569 (rnpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5569
Name
rnpA
Replicon chromosome
Genomic location 6263805 - 6264212 (- strand)

Cross-References

RefSeq NP_254256.1
GI 15600762
Affymetrix PA5569_rnpA_at
DNASU PaCD00007323
Entrez 877910
GenBank AAG08954.1
INSDC AAG08954.1
NCBI Locus Tag PA5569
protein_id(GenBank) gb|AAG08954.1|AE004968_8|gnl|PseudoCAP|PA5569
TIGR NTL03PA05570
UniParc UPI000013443A
UniProtKB Acc Q9HT05
UniProtKB ID RNPA_PSEAE
UniRef100 UniRef100_Q02DD9
UniRef50 UniRef50_P0A167
UniRef90 UniRef90_Q02DD9

Product

Feature Type CDS
Coding Frame 1
Product Name
ribonuclease P protein component
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 12.19
Kyte-Doolittle Hydrophobicity Value -0.580
Molecular Weight (kDa) 15.3
Isoelectric Point (pI) 11.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 203 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005100 (481 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5569
Search term: rnpA

Human Homologs

References

Physical mapping and nucleotide sequence of the rnpA gene that encodes the protein component of ribonuclease P in Escherichia coli.
Hansen FG, Hansen EB, Atlung T
Gene 1985;38(1-3):85-93
PubMed ID: 2415431
Genes and their organization in the replication origin region of the bacterial chromosome.
Ogasawara N, Yoshikawa H
Mol Microbiol 1992 Mar;6(5):629-34
PubMed ID: 1552862
Expression of C5 protein, the protein component of Escherichia coli RNase P, from the tac promoter.
Park BH, Choi YN, Park JW, Sim S, Gil MC, Kim S, Kim M, Lee Y
Mol Cells 1998 Feb 28;8(1):96-100
PubMed ID: 9571638