Pseudomonas aeruginosa PAO1, PA0105 (coxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0105
Name
coxB
Synonym: coII
Replicon chromosome
Genomic location 127378 - 128502 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248795.1
GI 15595303
Affymetrix PA0105_coxB_at
Entrez 881940
GenBank AAG03495.1
INSDC AAG03495.1
NCBI Locus Tag PA0105
protein_id(GenBank) gb|AAG03495.1|AE004449_4|gnl|PseudoCAP|PA0105
TIGR NTL03PA00106
UniParc UPI00000C4F3A
UniProtKB Acc Q9I727
UniProtKB ID Q9I727_PSEAE
UniRef100 UniRef100_Q9I727
UniRef50 UniRef50_Q4KKM0
UniRef90 UniRef90_Q9I727

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c oxidase, subunit II
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -3.78
Kyte-Doolittle Hydrophobicity Value -0.092
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 416 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000103 (511 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0105
Search term: coxB

Human Homologs

Ensembl 107, assembly GRCh38.p13
mitochondrially encoded cytochrome c oxidase II [Source:HGNC Symbol;Acc:HGNC:7421]
E-value: 8.5e-33
Percent Identity: 32.3

References

Structure at 2.8 A resolution of cytochrome c oxidase from Paracoccus denitrificans.
Iwata S, Ostermeier C, Ludwig B, Michel H
Nature 1995 Aug;376(6542):660-9
PubMed ID: 7651515
Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment.
Ostermeier C, Harrenga A, Ermler U, Michel H
Proc. Natl. Acad. Sci. U.S.A. 1997 Sep;94(20):10547-53
PubMed ID: 9380672