Pseudomonas aeruginosa PAO1, PA0219

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0219
Name
Replicon chromosome
Genomic location 247219 - 248709 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_248910.1
GI 15595416
Affymetrix PA0219_at
Entrez 879237
GenBank AAG03608.1
INSDC AAG03608.1
NCBI Locus Tag PA0219
protein_id(GenBank) gb|AAG03608.1|AE004460_1|gnl|PseudoCAP|PA0219
TIGR NTL03PA00220
UniParc UPI00000C4FA2
UniProtKB Acc Q9I6R9
UniProtKB ID Q9I6R9_PSEAE
UniRef100 UniRef100_U8MJD1
UniRef50 UniRef50_C9YAW5
UniRef90 UniRef90_A0A077JPA1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable aldehyde dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -10.41
Kyte-Doolittle Hydrophobicity Value -0.036
Molecular Weight (kDa) 53.6
Isoelectric Point (pI) 5.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 604 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000218 (401 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0219

Human Homologs

Ensembl 107, assembly GRCh38.p13
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.1e-108
Percent Identity: 44.9
Ensembl 107, assembly GRCh38.p13
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.1e-108
Percent Identity: 44.9
Ensembl 107, assembly GRCh38.p13
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.1e-108
Percent Identity: 44.9

References

Cloning an Escherichia coli gene encoding a protein remarkably similar to mammalian aldehyde dehydrogenases.
Heim R, Strehler EE
Gene 1991 Mar 1;99(1):15-23
PubMed ID: 1840553