Pseudomonas aeruginosa PAO1, PA0230 (pcaB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0230
|
| Name |
pcaB
|
| Replicon | chromosome |
| Genomic location | 259784 - 261163 (+ strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_248921.1 |
| GI | 15595427 |
| Affymetrix | PA0230_pcaB_at |
| Entrez | 881957 |
| GenBank | AAG03619.1 |
| INSDC | AAG03619.1 |
| NCBI Locus Tag | PA0230 |
| protein_id(GenBank) | gb|AAG03619.1|AE004461_2|gnl|PseudoCAP|PA0230 |
| TIGR | NTL03PA00231 |
| UniParc | UPI00000C4FAD |
| UniProtKB Acc | Q9I6Q8 |
| UniProtKB ID | PCAB_PSEAE |
| UniRef100 | UniRef100_Q9I6Q8 |
| UniRef50 | UniRef50_P32427 |
| UniRef90 | UniRef90_Q9I6Q8 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
3-carboxy-cis,cis-muconate cycloisomerase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -6.52 |
| Kyte-Doolittle Hydrophobicity Value | 0.039 |
| Molecular Weight (kDa) | 49.1 |
| Isoelectric Point (pI) | 6.24 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 634 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000229 (519 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0230
Search term: pcaB
Search term: 3-carboxy-cis,cis-muconate cycloisomerase
|
Human Homologs
References
|
3-Carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida is homologous to the class II fumarase family: a new reaction in the evolution of a mechanistic motif.
Williams SE, Woolridge EM, Ransom SC, Landro JA, Babbitt PC, Kozarich JW
Biochemistry 1992 Oct 13;31(40):9768-76
PubMed ID: 1390752
|