Pseudomonas aeruginosa PAO1, PA1084 (flgI)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
Locus Tag
Replicon chromosome
Genomic location 1169822 - 1170931 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs


RefSeq NP_249775.1
GI 15596281
Affymetrix PA1084_flgI_at
DNASU PaCD00006501
Entrez 878536
GenBank AAG04473.1
INSDC AAG04473.1
NCBI Locus Tag PA1084
protein_id(GenBank) gb|AAG04473.1|AE004539_15|gnl|PseudoCAP|PA1084
UniParc UPI000012A932
UniProtKB Acc Q9I4P5
UniRef100 UniRef100_A6V9B1
UniRef50 UniRef50_P58203
UniRef90 UniRef90_A6V9B1


Feature Type CDS
Coding Frame 1
Product Name
flagellar P-ring protein precursor FlgI
Product Name Confidence: Class 2
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) 0.96
Kyte-Doolittle Hydrophobicity Value 0.129
Molecular Weight (kDa) 38.2
Isoelectric Point (pI) 7.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Host Organism
Reference 14617143

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 243 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001046 (535 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA1084
Search term: flgI

Human Homologs


Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
The flaFIX gene product of Salmonella typhimurium is a flagellar basal body component with a signal peptide for export.
Homma M, Komeda Y, Iino T, Macnab RM
J Bacteriol 1987 Apr;169(4):1493-8
PubMed ID: 3549691
L-, P-, and M-ring proteins of the flagellar basal body of Salmonella typhimurium: gene sequences and deduced protein sequences.
Jones CJ, Homma M, Macnab RM
J Bacteriol 1989 Jul;171(7):3890-900
PubMed ID: 2544561
Molecular cloning of two Pseudomonas flagellin genes and basal body structural genes.
Winstanley C, Morgan JA, Pickup RW, Saunders JR
Microbiology (Reading) 1994 Aug;140 ( Pt 8):2019-31
PubMed ID: 7921252
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994