Pseudomonas aeruginosa PAO1, PA1087 (flgL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1087
Name
flgL
Synonym: flaK
Replicon chromosome
Genomic location 1174240 - 1175559 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249778.1
GI 15596284
Affymetrix PA1087_flgL_at
Entrez 877768
GenBank AAG04476.1
INSDC AAG04476.1
NCBI Locus Tag PA1087
protein_id(GenBank) gb|AAG04476.1|AE004539_18|gnl|PseudoCAP|PA1087
TIGR NTL03PA01088
UniParc UPI00000C5241
UniProtKB Acc Q9I4P2
UniProtKB ID Q9I4P2_PSEAE
UniRef100 UniRef100_Q9I4P2
UniRef50 UniRef50_Q9I4P2
UniRef90 UniRef90_Q9I4P2

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar hook-associated protein type 3 FlgL
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -17.50
Kyte-Doolittle Hydrophobicity Value -0.355
Molecular Weight (kDa) 46.8
Isoelectric Point (pI) 4.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 247 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001049 (533 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1087
Search term: flgL

Human Homologs

References

Flagellar hook and hook-associated proteins of Salmonella typhimurium and their relationship to other axial components of the flagellum.
Homma M, DeRosier DJ, Macnab RM
J Mol Biol 1990 Jun 20;213(4):819-32
PubMed ID: 2193164
Genetic and molecular characterization of the polar flagellum of Vibrio parahaemolyticus.
McCarter LL
J Bacteriol 1995 Mar;177(6):1595-609
PubMed ID: 7883718