Pseudomonas aeruginosa PAO1, PA1146

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1146
Name
Replicon chromosome
Genomic location 1237551 - 1238732 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249837.1
GI 15596343
Affymetrix PA1146_at
Entrez 878737
GenBank AAG04535.1
INSDC AAG04535.1
NCBI Locus Tag PA1146
protein_id(GenBank) gb|AAG04535.1|AE004544_7|gnl|PseudoCAP|PA1146
TIGR NTL03PA01147
UniParc UPI00000C5273
UniProtKB Acc Q9I4I9
UniProtKB ID Q9I4I9_PSEAE
UniRef100 UniRef100_Q9I4I9
UniRef50 UniRef50_A0A021X8S6
UniRef90 UniRef90_Q9I4I9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable iron-containing alcohol dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -6.27
Kyte-Doolittle Hydrophobicity Value 0.089
Molecular Weight (kDa) 41.9
Isoelectric Point (pI) 6.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 470 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001106 (1358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1146

Human Homologs

References

Metabolic pathway for biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from 4-hydroxybutyrate by Alcaligenes eutrophus.
Valentin HE, Zwingmann G, Schönebaum A, Steinbüchel A
Eur J Biochem 1995 Jan 15;227(1-2):43-60
PubMed ID: 7851418
Purification of 1,3-propanediol dehydrogenase from Citrobacter freundii and cloning, sequencing, and overexpression of the corresponding gene in Escherichia coli.
Daniel R, Boenigk R, Gottschalk G
J Bacteriol 1995 Apr;177(8):2151-6
PubMed ID: 7721705