Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1195
|
Name |
ddaH
|
Replicon | chromosome |
Genomic location | 1296334 - 1297098 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_249886.1 |
GI | 15596392 |
Affymetrix | PA1195_at |
Entrez | 883112 |
GenBank | AAG04584.1 |
INSDC | AAG04584.1 |
NCBI Locus Tag | PA1195 |
protein_id(GenBank) | gb|AAG04584.1|AE004549_11|gnl|PseudoCAP|PA1195 |
TIGR | NTL03PA01196 |
UniParc | UPI0000033BA5 |
UniProtKB Acc | Q9I4E3 |
UniProtKB ID | DDAH_PSEAE |
UniRef100 | UniRef100_Q9I4E3 |
UniRef50 | UniRef50_Q9I4E3 |
UniRef90 | UniRef90_Q9I4E3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
dimethylarginine dimethylaminohydrolase DdaH
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | -6.46 |
Kyte-Doolittle Hydrophobicity Value | -0.229 |
Molecular Weight (kDa) | 28.5 |
Isoelectric Point (pI) | 5.42 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3RHY | HYDROLASE | 04/12/11 | Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine | Pseudomonas aeruginosa | 2.18 | X-RAY DIFFRACTION | 100.0 |
1H70 | HYDROLASE | 06/30/01 | DDAH FROM PSEUDOMONAS AERUGINOSA. C249S MUTANT COMPLEXED WITH CITRULLINE | PSEUDOMONAS AERUGINOSA | 1.8 | X-RAY DIFFRACTION | 99.6 |
3BPB | HYDROLASE | 12/18/07 | Crystal structure of the dimethylarginine dimethylaminohydrolase H162G adduct with S-methyl-L-thiocitrulline | Pseudomonas aeruginosa | 2.81 | X-RAY DIFFRACTION | 99.6 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 96 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001153 (298 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1195
Search term: ddaH
Search term: dimethylarginine dimethylaminohydrolase DdaH
|
Ensembl
110, assembly
GRCh38.p14
|
dimethylarginine dimethylaminohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:2715]
E-value:
1.8e-26
Percent Identity:
30.8
|
Cloning and sequencing of cDNA encoding NG,NG-dimethylarginine dimethylaminohydrolase from rat kidney.
Kimoto M, Sasakawa T, Tsuji H, Miyatake S, Oka T, Nio N, Ogawa T
Biochim Biophys Acta 1997 Jan 4;1337(1):6-10
PubMed ID: 9003431
|
DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
Lundgren BR, Bailey FJ, Moley G, Nomura CT
J Bacteriol 2017 Apr 15;199(8)
PubMed ID: 28167521
|
Characterization and manipulation of the Pseudomonas aeruginosa dimethylarginine dimethylaminohydrolase monomer--dimer equilibrium.
Plevin MJ, Magalhães BS, Harris R, Sankar A, Perkins SJ, Driscoll PC
J Mol Biol 2004 Jul 30;341(1):171-84
PubMed ID: 15312771
|