Pseudomonas aeruginosa PAO1, PA1238

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1238
Name
Synonym: opmJ
Replicon chromosome
Genomic location 1339079 - 1340527 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249929.1
GI 15596435
Affymetrix PA1238_at
Entrez 881203
GenBank AAG04627.1
INSDC AAG04627.1
NCBI Locus Tag PA1238
protein_id(GenBank) gb|AAG04627.1|AE004553_4|gnl|PseudoCAP|PA1238
TIGR NTL03PA01239
UniParc UPI00000C52C7
UniProtKB Acc Q9I4A0
UniProtKB ID Q9I4A0_PSEAE
UniRef100 UniRef100_Q9I4A0
UniRef50 UniRef50_Q9I4A0
UniRef90 UniRef90_Q9I4A0

Product

Feature Type CDS
Coding Frame 1
Product Name
probable outer membrane component of multidrug efflux pump
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 14.06
Kyte-Doolittle Hydrophobicity Value -0.320
Molecular Weight (kDa) 52.3
Isoelectric Point (pI) 10.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 276 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001190 (378 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1238

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa.
Köhler T, Michéa-Hamzehpour M, Henze U, Gotoh N, Curty LK, Pechère JC
Mol Microbiol 1997 Jan;23(2):345-54
PubMed ID: 9044268