Pseudomonas aeruginosa PAO1, PA1782

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1782
Name
Replicon chromosome
Genomic location 1928894 - 1930489 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_250473.1
GI 15596979
Affymetrix PA1782_at
Entrez 878606
GenBank AAG05171.1
INSDC AAG05171.1
NCBI Locus Tag PA1782
protein_id(GenBank) gb|AAG05171.1|AE004604_1|gnl|PseudoCAP|PA1782
TIGR NTL03PA01783
UniParc UPI00000C5495
UniProtKB Acc Q9I2W0
UniProtKB ID Q9I2W0_PSEAE
UniRef100 UniRef100_X6XIU5
UniRef50 UniRef50_Q1ICL8
UniRef90 UniRef90_Q02KS3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable serine/threonine-protein kinase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -4.84
Kyte-Doolittle Hydrophobicity Value -0.188
Molecular Weight (kDa) 58.9
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 444 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000073 (1354 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1782

Human Homologs

Ensembl 110, assembly GRCh38.p14
protein kinase cAMP-activated catalytic subunit gamma [Source:HGNC Symbol;Acc:HGNC:9382]
E-value: 3.0e-15
Percent Identity: 29.8

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295