Pseudomonas aeruginosa PAO1, PA3166 (pheA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3166
Name
pheA
Replicon chromosome
Genomic location 3554157 - 3555254 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251856.1
GI 15598362
Affymetrix PA3166_pheA_at
DNASU PaCD00007393
Entrez 882699
GenBank AAG06554.1
INSDC AAG06554.1
NCBI Locus Tag PA3166
protein_id(GenBank) gb|AAG06554.1|AE004740_7|gnl|PseudoCAP|PA3166
TIGR NTL03PA03166
UniParc UPI00000C5931
UniProtKB Acc Q9HZ67
UniProtKB ID PHEA_PSEAE
UniRef100 UniRef100_Q9HZ67
UniRef50 UniRef50_Q9HZ67
UniRef90 UniRef90_Q9HZ67

Product

Feature Type CDS
Coding Frame 1
Product Name
chorismate mutase
Product Name Confidence: Class 2
Synonyms prephenate dehydratase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.74
Kyte-Doolittle Hydrophobicity Value -0.227
Molecular Weight (kDa) 40.6
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 592 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002449 (553 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3166
Search term: pheA
Search term: chorismate mutase

Human Homologs

References

Cloning, sequencing, and expression of the P-protein gene (pheA) of Pseudomonas stutzeri in Escherichia coli: implications for evolutionary relationships in phenylalanine biosynthesis.
Fischer RS, Zhao G, Jensen RA
J Gen Microbiol 1991 Jun;137(6):1293-301
PubMed ID: 1919506
A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling.
Xie G, Bonner CA, Jensen RA
J. Mol. Evol. 1999 Jul;49(1):108-21
PubMed ID: 10368439