Pseudomonas aeruginosa PAO1, PA3166 (pheA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA3166
|
| Name |
pheA
|
| Replicon | chromosome |
| Genomic location | 3554157 - 3555254 (- strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_251856.1 |
| GI | 15598362 |
| Affymetrix | PA3166_pheA_at |
| DNASU | PaCD00007393 |
| Entrez | 882699 |
| GenBank | AAG06554.1 |
| INSDC | AAG06554.1 |
| NCBI Locus Tag | PA3166 |
| protein_id(GenBank) | gb|AAG06554.1|AE004740_7|gnl|PseudoCAP|PA3166 |
| TIGR | NTL03PA03166 |
| UniParc | UPI00000C5931 |
| UniProtKB Acc | Q9HZ67 |
| UniProtKB ID | PHEA_PSEAE |
| UniRef100 | UniRef100_Q9HZ67 |
| UniRef50 | UniRef50_Q9HZ67 |
| UniRef90 | UniRef90_Q9HZ67 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
chorismate mutase
|
| Synonyms |
prephenate dehydratase |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -5.74 |
| Kyte-Doolittle Hydrophobicity Value | -0.227 |
| Molecular Weight (kDa) | 40.6 |
| Isoelectric Point (pI) | 6.28 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 592 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG002449 (553 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA3166
Search term: pheA
Search term: chorismate mutase
|
Human Homologs
References
|
Cloning, sequencing, and expression of the P-protein gene (pheA) of Pseudomonas stutzeri in Escherichia coli: implications for evolutionary relationships in phenylalanine biosynthesis.
Fischer RS, Zhao G, Jensen RA
J Gen Microbiol 1991 Jun;137(6):1293-301
PubMed ID: 1919506
|
|
A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling.
Xie G, Bonner CA, Jensen RA
J. Mol. Evol. 1999 Jul;49(1):108-21
PubMed ID: 10368439
|