Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3677
|
Name |
mexJ
|
Replicon | chromosome |
Genomic location | 4119270 - 4120373 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_252367.1 |
GI | 15598873 |
Affymetrix | PA3677_at |
Entrez | 879603 |
GenBank | AAG07065.1 |
INSDC | AAG07065.1 |
NCBI Locus Tag | PA3677 |
protein_id(GenBank) | gb|AAG07065.1|AE004787_5|gnl|PseudoCAP|PA3677 |
TIGR | NTL03PA03677 |
UniParc | UPI00000C5AB5 |
UniProtKB Acc | Q9HXW3 |
UniProtKB ID | Q9HXW3_PSEAE |
UniRef100 | UniRef100_A0A069Q6H1 |
UniRef50 | UniRef50_Q4KHJ5 |
UniRef90 | UniRef90_W0YTY2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MexJ
|
Synonyms |
probable RND efflux membrane fusion protein precursor |
Evidence for Translation | |
Charge (pH 7) | 6.19 |
Kyte-Doolittle Hydrophobicity Value | -0.238 |
Molecular Weight (kDa) | 40.1 |
Isoelectric Point (pI) | 9.81 |
Individual Mappings | |
Additional evidence for subcellular localization |
Identified using the Resistance Gene Identifier (RGI)
Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
MexJ | MexJ is the membrane fusion protein of the MexJK multidrug efflux protein. [PMID:12193619] | ARO:3003692 | protein homolog model | Perfect | 697.2 | 100.0 | 3.2.5 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 443 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000154 (998 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3677
Search term: mexJ
Search term: MexJ
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
The MexJK efflux pump of Pseudomonas aeruginosa requires OprM for antibiotic efflux but not for efflux of triclosan.
Chuanchuen R, Narasaki CT, Schweizer HP
J Bacteriol 2002 Sep;184(18):5036-44
PubMed ID: 12193619
|